13573-34-7Relevant academic research and scientific papers
Direct synthesis of 2,4,5-trisubstituted imidazoles and di/tri-substituted pyrimidines via cycloadditions of α,β-unsaturated ketones/aldehydes and N′-hydroxyl imidamides
Wu, Ping,Zhang, Xueguo,Chen, Baohua
, p. 1103 - 1107 (2019)
An efficient route for the synthesis of 5-acetylimidazoles and di/trisubstituted pyrimidines via iron-catalyzed cross-dehydrogenative coupling (CDC), with excellent tolerance and yields, has been developed. In this report, α,β-unsaturated aldehydes/ketones and N′-hydroxyl imidamides undergo [3+2] and [3+3] cycloadditions in two processes, involving iron-mediated Michael reaction, Robinson Annulation and 1,5-electrocyclization.
Microwave-assisted simple, one-pot, four-component synthesis of 2,4,6-triarylpyrimidines under solvent-free conditions
Adib, Mehdi,Mahmoodi, Niusha,Mahdavi, Mohammad,Bijanzadeh, Hamid Reza
, p. 9365 - 9368 (2006)
2,4,6-Triarylpyrimidines are synthesized via a simple, one-pot, four-component reaction between aryl methyl ketones, benzaldehydes, aromatic nitriles, and hydroxylamine under microwave irradiation and solvent-free conditions in good to excellent yields.
Preparation method of 2,4,6-triaryl-substituted-pyrimidine compounds
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Paragraph 0056-0059, (2019/10/01)
The invention discloses a preparation method of 2,4,6-triaryl-substituted-pyrimidine compounds. The preparation method includes the following steps that aromatic aldehyde compounds shown in the formula (I), aromatic ketone compounds shown in the formula (
Transition-metal-free selective pyrimidines and pyridines formation from aromatic ketones, aldehydes and ammonium salts
Chen, Jinjin,Meng, Huanxin,Zhang, Feng,Xiao, Fuhong,Deng, Guo-Jun
supporting information, p. 5201 - 5206 (2019/10/11)
An efficient synthesis of pyrimidines and pyridines has been developed from readily available aromatic ketones, aldehydes and ammonium salts under transition-metal-free conditions. In this strategy, ammonium salts were used as nitrogen sources and only wa
Secondary amines immobilized inside magnetic mesoporous materials as a recyclable basic and oxidative heterogeneous nanocatalyst for the synthesis of trisubstituted pyrimidine derivatives
Aryan, Reza,Beyzaei, Hamid,Nojavan, Masoomeh,Dianatipour, Tahereh
, p. 4417 - 4431 (2016/07/06)
A novel magnetic MCM-41 nanocomposite-based catalyst is reported for the first time in the multicomponent synthesis of trisubstituted pyrimidines in which piperazine is immobilized inside the mesochannels of magnetic MCM-41 as an organic base (α-Fe2
Synthesis of some new 2,4,6-trisubstituted phenyl pyrimidines using 4-nitro and 4-fluorophenacyldimethylsulfonium bromides with aromatic aldehydes
Gupta,Gupta,Gupta, Vandana,Gupta
, p. 299 - 302 (2008/03/11)
4-Nitrophenacyldimethylsulfonium bromide and 4- fluorophenacyldimethylsulfonium bromide have been prepared by the reaction of dimethyl sulfide with 4-substitutedphenacyl bromide in benzene at reflux temperature under nitrogen atmosphere. These sulfonium s
