1357575-27-9

Basic information

• Product Name: N-(4-((R)-4-((2-(tert-butyldimethylsilyloxy)ethyl)(methyl)amino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)-4-(4-((R)-(4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)benzamide
• Synonyms: N-(4-((R)-4-((2-(tert-butyldimethylsilyloxy)ethyl)(methyl)amino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)-4-(4-((R)-(4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)benzamide
• CAS NO: 1357575-27-9
• Molecular Weight: 1059.81
• Mol File: 1357575-27-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-((R)-4-((2-(tert-butyldimethylsilyloxy)ethyl)(methyl)amino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)-4-(4-((R)-(4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-((R)-4-((2-(tert-butyldimethylsilyloxy)ethyl)(methyl)amino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)-4-(4-((R)-(4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)benzamide(1357575-27-9)
• EPA Substance Registry System: N-(4-((R)-4-((2-(tert-butyldimethylsilyloxy)ethyl)(methyl)amino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)-4-(4-((R)-(4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)benzamide(1357575-27-9)

Safety Data

• Hazardous Substances Data: 1357575-27-9(Hazardous Substances Data)

Upstream product

• 1357575-13-3 (4'-chlorobiphenyl-2-yl)(piperidin-4-yl)methanol 
• 1357575-11-1 (R)-ethyl 4-(4-((4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)benzoate 
• 1357575-02-0 (R)-methyl 4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butanoate 
• 1357575-01-9 (R)-methyl 3-(benzyloxycarbonylamino)-4-(phenylthio)butanoate 
• 1357575-08-6 tert-butyl 4-[(4'-chlorobiphenyl-2-yl)(hydroxy)methyl]piperidine-1-carboxylate 
• 1357575-04-2 (R)-methyl 3-amino-4-(phenylthio)butanoate, trifluoroacetic acid salt 
• 2358-41-0 1-fluoro-2-[(trifluoromethyl)sulfonyl]benzene 
• 1027345-08-9 4-fluoro-3-[(trifluoromethyl)sulfonyl]benzenesulfonamide 
• 583-53-9 2,3-dibromobenzene 
• 1679-18-1 4-Chlorophenylboronic acid 
• 179526-95-5 2-bromo-4,4’-dichloro-1,1’-biphenyl 
• 1357575-44-0 (R)-4-((4-oxo-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide 
• 1357575-28-0 (R)-4-(4-((4'-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)benzoic acid 
• 1357575-29-1 (R)-4-(4-((2-(tert-butyldimethylsilyloxy)ethyl)(methyl)amino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)benzenesulfonamide 

Downstream Products

• 1357576-48-7 4-(4-((R)-(4’-chlorobiphenyl-2-yl)(hydroxy)methyl)piperidin-1-yl)-N-(4-((R)-4-((2-hydroxyethyl)(methyl)amino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide 

Relevant articles and documents

CHEMICAL COMPOUNDS

The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.