135758-71-3

Upstream product

• 76939-53-2 α-D-glucosyl-1-phosphate 
• 127-09-3 sodium acetate 
• 3554-77-6 Acetic acid (2R,3S,4R,5R,6S)-3,4,5-trimethoxy-6-methoxymethyl-tetrahydro-pyran-2-yl ester 
• 3554-77-6 Acetic acid (2S,3S,4R,5R,6S)-3,4,5-trimethoxy-6-methoxymethyl-tetrahydro-pyran-2-yl ester 
• 2280-44-6 D-Glucose 
• 507-09-5 tiolacetic acid 
• 530-26-7 D-Mannose 
• 123-54-6 acetylacetone 
• 6564-72-3 2,3,4,6-tetra-O-benzyl-D-glucopyranose 
• 64-19-7 acetic acid 
• 56822-48-1 (2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-yl acetate 

Downstream Products

• 709-50-2 methyl beta-D-glucopyranoside 

Relevant academic research and scientific papers

A three-enzyme cascade reaction through positional assembly of enzymes in a polymersome nanoreactor

Porous polymersomes based on block copolymers of isocyanopeptides and styrene have been used to anchor enzymes at three different locations, namely, in their lumen (glucose oxidase, GOx), in their bilayer membrane (Candida antarctica lipase B, CalB) and o

Synthesis of l-glucose and l-galactose derivatives from d-sugars

An efficient route to prepare l-glucose and l-galactose is described. The l-sugars are achieved by using the strategy of switching the functional groups at C1 and C5 of d-glucose and d-mannose. The oxidation and reduction of the silyl enol ether at C1 and the lead(IV) tetraacetate mediated oxidative decarboxylation at C5 are the key steps. l-Glucose and l-galactose are prepared in a convenient and inexpensive way.

Beta-D-glucose short-chain fatty acid ester compound as well as preparation method and application thereof

The invention discloses a beta-D-glucose short-chain fatty acid ester compound as well as a preparation method and application thereof, and belongs to the technical field of organic synthesis. The compound is a compound shown as a formula I, or a stereoisomer, a pharmaceutically acceptable salt, a solvate or a prodrug of the compound shown as the formula I. The formula is as shown in the description, wherein R is a methyl group, an ethyl group, a propyl group, a propylene group, an isopropylidene group, a butyl group, a butylidene group, an isobutylidene group, an amyl group, a pentylidene group or an isoamylidene group. The compound has potential prevention and treatment effects on diabetes, hyperlipidemia, atherosclerosis, Alzheimer's disease, cardiovascular and cerebrovascular diseases,inflammation, tumors and depression.

Selective anomeric acetylation of unprotected sugars in water

High yielding selective acetylation of only the anomeric hydroxyl of unprotected sugars is possible in aqueous solution using 2-chloro-1,3-dimethylimidazolinium chloride (DMC), thioacetic acid, and a suitable base. The reaction, which may be performed on a multi-gram scale, is stereoselective for sugars that possess a hydroxyl group at position-2, exclusively yielding the 1,2-trans products. The use of an iterative reagent addition procedure allows the use of sodium carbonate as the base, avoiding the formation of triethylammonium salts, which may hamper product purification. The glycosyl acetate products may be used as donor substrates for glycosidase-catalysed synthesis. The crude aqueous acetylation reaction mixture may also be used for this purpose.

In situ proton NMR study of acetyl and formyl group migration in mono-O-acyl D-glucose

Acetyl and formyl group migration, mutarotation, and hydrolysis of mono-O-acylated glucose are studied by in situ 1D and 2D 1H NMR spectroscopy. α-D-Glucosyl-1-acetate and α-D-glucosyl-1 -formate serve as sole starting materials. They are gener

One-step stereocontrolled synthesis of α-anomeric carboxylic acid esters from unprotected glycosyl donors: A water-soluble aspirin pro-drug analogue

The reaction of 2-(3-methoxypyridyl) β-D-gluco- and D-galactopyranosides with various carboxylic acids affords the corresponding α-1-esters in high yields. Aspirin can be solubilized in water as the α-D-galactopyranosyl ester.

Simple Synthesis of β-D-Glucosyl Esters

Acylation of 2,3,4,6-tetra-O-benzyl-α-D-glucopyranose (1) with benzoyl chloride and triethylamine was found to give 1-O-benzoyl-2,3,4,6-tetra-O-benzyl-α-D-glucopyranose (2) and 1-O-benzoyl-2,3,4,6-tetra-O-benzyl-β-D-glucopyranose (3) in a ratio of 2:9 whi

THE OCCURRENCE OF L-GALACTOSE IN SNAIL GALACTANS

The occurrence of L-galactose (L-Gal) was investigated in twelve preparations of snail galactans from nine different species.L-Gal (11-15percent) was found not only in members of the family Helicidae, a highly developed group among the Pulmonata, but was detected also in a galactan of the oldest phylogenetic subclass of snails in the Prosobranchiata.To determine the position of the L-Gal residues, the galactans of Arianta arbustorum, Cepaea nemoralis, and Helix pomatia were methylated and hydrolysed, and the partially methylated Gal derivatives were isolated.Each derivative was O-demethylated and the ratio of D- and L-galactose was determined by g.l.c. of the trifluoroacetylated methyl glycosides using a chiral stationary phase.L-Gal (22-34percent) was detected only in the tetra-O-methyl fractions, and hence L-Gal occupies exclusively terminal non-reducing positions.