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  • 4-Iodoimidazole CAS 71759-89-2 1H-Imidazole,5-iodo- CAS no 71759-89-2 5-Iodo-1H-imidazole

    Cas No: 71759-89-2

  • USD $ 3.5-5.0 / Kiloliter

  • 5 Kiloliter

  • 3000 Metric Ton/Month

  • Chemwill Asia Co., Ltd.
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71759-89-2 Usage

Chemical Properties

White Solid


suzuki reaction

Check Digit Verification of cas no

The CAS Registry Mumber 71759-89-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,7,5 and 9 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 71759-89:
162 % 10 = 2
So 71759-89-2 is a valid CAS Registry Number.

71759-89-2 Well-known Company Product Price

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  • Alfa Aesar

  • (L20184)  4(5)-Iodoimidazole, 94%   

  • 71759-89-2

  • 250mg

  • 462.0CNY

  • Detail
  • Alfa Aesar

  • (L20184)  4(5)-Iodoimidazole, 94%   

  • 71759-89-2

  • 1g

  • 1574.0CNY

  • Detail
  • Alfa Aesar

  • (L20184)  4(5)-Iodoimidazole, 94%   

  • 71759-89-2

  • 5g

  • 6204.0CNY

  • Detail
  • Aldrich

  • (L510513)  4-Iodoimidazole  AldrichCPR

  • 71759-89-2

  • L510513-1G

  • 321.75CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name 4-Iodoimidazole

1.2 Other means of identification

Product number -
Other names 1H-IMIDAZOLE,4-IODO

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71759-89-2 SDS

71759-89-2Relevant articles and documents

Preparation method of 4-iodo-1H-imidazole


Paragraph 0021-0026, (2020/04/17)

The invention provides a preparation method of 4-iodo-1H-imidazole. The preparation method comprises the following steps: (1) enabling imidazole, iodine and a cosolvent for promoting the solubility ofiodine in water to react under an alkaline condition in the presence of water as a solvent, after the reaction is finished, adjusting the pH value to 7-9, filtering out precipitated white solids, performing extraction, reduced pressure distillation to remove the solvent, and recrystallization on the filtrate to recover imidazole, concentrating the recrystallized mother liquor, and mixing the obtained white solids and the precipitated white solids to obtain a 4-iodo-1H-imidazole crude product, and (2) recrystallizing the 4-iodo-1H-imidazole crude product twice to obtain a white crystal 4-iodo-1H-imidazole pure product. The method has the advantages of simple process, high reaction yield, low production cost and recyclable raw materials.

Imidazo isoindole IDO1 inhibitor as well as preparation method and application thereof


Paragraph 0085; 0086; 0089; 0090, (2018/01/11)

The invention belongs to the field of medicine, and particularly relates to an imidazo isoindole IDO1 compound with structural characteristics of the formula (I) shown in the description as well as a three-dimensional isomer or a pharmaceutically acceptable salt thereof, a preparation method thereof and application thereof as an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor. An experiment result shows that the compound of the invention has a significant inhibition effect for the activity of IDO1, can effectively promote the proliferation of cells T, prevents initial cells T from being differentiated into adjustable cells T, can invert IDO1 mediating immunosuppression, can be used for treating relevant diseases with pathological features of an IDO1 mediating kynurenine metabolic way including cancers, virus infection, neurodegenerative diseases, cataracts, organ transplant rejection, depression, autoimmune diseases and the like.

Scope and Mechanistic Limitations of a Sonogashira Coupling Reaction on an Imidazole Backbone

Sandtorv, Alexander H.,Bj?rsvik, Hans-René

, p. 4658 - 4666 (2015/08/03)

A Sonogashira coupling reaction method to join terminal alkynes to the imidazole backbone was developed and investigated. The method exhibits good functional group tolerance and provides target 4-alkynylated imidazoles in 70-93% yield. The alkyne reagents were characterized by means of DFT calculations, from which electrostatic potential surfaces (EPS) were produced. A clear correlation between the EPS of the triple bond and the success of the coupling reaction was revealed. If the EPS is in range -94 to -105 kJmol-1 the coupling is successful. An unsuccessful class of reagents (alkynols) was made compatible by means of an auxiliary group (tert-butyldimethylsilyl). EPSs of these modified reagents then resembled those of the model and these auxiliary-assisted reagents then coupled successfully in excellent yields.

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