135840-32-3

Upstream product

• 88920-24-5 p-methoxybenzyloxy acetic acid 
• 186406-64-4 ((E)-(2R,6S)-2-Allyl-7-iodo-4,6-dimethyl-hept-3-enyloxy)-tert-butyl-dimethyl-silane 
• 135840-17-4 (2S,4S,5S)-4-isopropenyl-2-phenyl-5-(2-propenyl)-1,3-dioxacyclohexane 
• 135840-20-9 (2S,4E,6R)-6-(tert-butyldimethylsilyl)oxymethyl-2,4-dimethyl-4,8-nonadien-1-ol 
• 186406-54-2 (2S,4S,5S)-4-acetyl-2-phenyl-5-(2-propenyl)-1,3-dioxacyclohexane 
• 186406-53-1 (2S,4S,5S)-4-formyl-2-phenyl-5-(2-propenyl)-1,3-dioxacyclohexane 
• 135840-16-3 (2S,4S,5S)-4-hydroxymethyl-2-phenyl-5-(2-propenyl)-1,3-dioxacyclohexane 
• 135840-18-5 (1S,2S)-2-(tert-butyldimethylsilyl)oxymethyl-1-isopropenyl-4-pentenyl propanoate 
• 135840-19-6 (2S,4E,6R)-6-(tert-butyldimethylsilyl)oxymethyl-2,4-dimethyl-4,8-nonadienoic acid 
• 98265-80-6 (S)-2-benzyl 1-tert-butyl piperidine-1,2-dicarboxylate 
• 186406-59-7 (2R,3S,5R)-2,6-dibenzyloxy-3-methoxy-5-methyl-1-hexanol 
• 135840-31-2 (S)-1-[2-(4-Methoxy-benzyloxy)-acetyl]-piperidine-2-carboxylic acid 
• 135840-27-6 (2S,3S,5R)-2,6-dibenzyloxy-3-methoxy-5-methylhexanal 
• 186406-61-1 (2R,4S,5R,6S,8S,10E,12R)-12-(tert-butyldimethylsilyl)oxymethyl-4,6-dimethoxy-2,8,10-trimethyl-10,14-pentadecadiene-1,5-diol 

Relevant academic research and scientific papers

A Synthesis of C1-C22 Fragment of the Immunosuppressant FK 506. Stereoselective Construction of (E)-Trisubstituted Double Bond (C19-C20) via Ester-enolate Claisen Rearrangement

An ene-ester 5 prepared from L-malic acid was subjected to the ester-enolate Claisen rearrangement under Ireland's condition to give stereoselectively C16-C22 fragment 11 containing (E)-trisubstituted double bond which was further advanced to C1-C22 fragm