13598-51-1

Basic information

• Product Name: thiophosphoric acid
• Synonyms: thiophosphoric acid;PHOSPHOROTHIOICACID;phosphorothioic O,O,S-acid
• CAS NO: 13598-51-1
• Molecular Formula: H₃O₃PS
• Molecular Weight: 114.06
• Mol File: 13598-51-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 2.149g/cm³
• CAS DataBase Reference: thiophosphoric acid(CAS DataBase Reference)
• NIST Chemistry Reference: thiophosphoric acid(13598-51-1)
• EPA Substance Registry System: thiophosphoric acid(13598-51-1)

Safety Data

• Hazardous Substances Data: 13598-51-1(Hazardous Substances Data)

Usage

General Description

Thiophosphoric acid is a compound with the chemical formula H3PO3S, consisting of one phosphorus atom, three hydrogen atoms, and one sulfur atom. It is a highly reactive and unstable compound, and as such, it is not commonly found in a pure form. Thiophosphoric acid is used as an intermediate in the production of various thiophosphates and phosphorothioic acid derivatives, which are commonly employed as pesticides, herbicides, and insecticides. It is also used in the synthesis of pharmaceuticals and as a reagent in chemical reactions. Thiophosphoric acid is highly corrosive and toxic, and precautions should be taken when handling and working with this compound.

InChI:InChI=1/H3O3PS/c1-4(2,3)5/h(H3,1,2,3,5)

Upstream product

• 2404-52-6 thiophosphoryl fluoride 
• 7732-18-5 water 
• 3982-91-0 trichlorothiophosphine 
• 3931-89-3 thiophosphoryl(V) bromide 
• 25070-46-6 tetraphosphorus nonasulfide 
• 15857-57-5 tetraphosphorus decasulfide 
• 7647-01-0 hydrogenchloride 
• 7601-90-3 perchloric acid 
• 13977-59-8 potassium dihydrogenmonothiophosphate 
• 15834-33-0 dithioorthophosphoric acid 

Related news

The thermal stability and antiwear performance of some thiophosphoric acid (cas 13598-51-1) derivatives09/03/2019

In order to study the relationship between the thermal stability and antiwear performance of metal-free phosphorus-sulphur compounds, some mono- and dithiophosphoric acid -O,O,S- triesters with specifically modified structures were synthesized and characterized by elemental analysis and 31P NMR ...detailed

Original paperInhibition of non-specific leukocyte esterase activity. Absence of monocyte esterase activity due to phosphoric and thiophosphoric acid (cas 13598-51-1) ester intoxication09/02/2019

In vitro evaluation of the effect of five insecticidal phosphoric and 11 thiophosphoric acid esters on different, non-specific human leukocytes esterases indicated that most of the organic phosphor compounds studied inhibited the activity of neutral α-naphthylacetate esterase, α-naphthylbutyry...detailed

A new synthesis of thiophosphoric acid (cas 13598-51-1) esters with a C-S-P bond09/01/2019

Various S-substituted thiosuccinimides 1a-d and thiophthalimides 2a-d were found to react with trialkylphosphites according to a Michaelis-Arbuzov type mechanism. This provides an efficient way to prepare thiophosphoric acid esters, particularly thiophospholipids, with a C-S-P bond.detailed

Short communicationActivation of spleen cell lytic activity by the alkaloid thiophosphoric acid (cas 13598-51-1) derivative: Ukrain08/31/2019

Ukrain is a semisynthetic compound consisting of alkaloids from Chelidonium majus L. conjugated to thiophosphoric acid, with immunomodulatory and therapeutic properties in cancer patients. The present in vitro studies demonstrate that Ukrain is an effective biological response modifier in that i...detailed

Synthesis and biological evaluation of phosphonic and thiophosphoric acid (cas 13598-51-1) derivatives of lysophosphatidic acid08/26/2019

Using an N-oleoyl ethanolamide scaffold, a series of phosphate polar head group analogues of LPA comprised of various α-substituted phosphonates and thiophosphates was prepared. In a broken cell GTP[γ35S] binding assay, agonist activity was evaluated at the three LPA receptors of the endotheli...detailed

Relevant articles and documents

Bio-based alkyl thiophosphoric acid or derivative thereof and preparation method and application of bio-based alkyl thiophosphoric acid or derivative thereof

The invention discloses a bio-based alkyl thiophosphoric acid or a derivative thereof and a preparation method and application of the bio-based alkyl thiophosphoric acid or the derivative of the bio-based alkyl thiophosphoric acid. The bio-based alkyl thiophosphoric acid is of the structure shown in the formula (I), wherein at least one of R1, R2, X, Y, Z, W and M comes from bio-based raw materials, R1 and R2 independently are alkyl, hydroxyl, carbonyl or heteroatom, at least one of X, Y, Z and W contains sulphur atoms, the rest is selected from O and S atoms, and M is H or a derivative group of a molecule of the structure shown in the formula (I). In the synthesis process of the bio-based alkyl thiophosphoric acid or the derivative of the bio-based alkyl thiophosphoric acid, at least one raw material is selected from bio-based raw materials, namely natural and renewable raw materials, and the bio-based alkyl thiophosphoric acid or the derivative of the bio-based alkyl thiophosphoric acid has the advantages that pollution is avoided, environmental friendliness is achieved, the raw materials are renewable and energy is saved, and can be widely applied in the fields of lubricating oil, lubricating grease, mine flotation agent, pesticide, fire retardant, rubber accelerators and the like.