136-34-5

Basic information

• Product Name: N-(thiophen-2-yl)benzamide
• CAS NO: 136-34-5
• Molecular Formula: C₁₁H₉NOS
• Molecular Weight: 203.2603
• Mol File: 136-34-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 250.9°C at 760 mmHg
• Flash Point: 105.6°C
• Density: 1.288g/cm³
• Vapor Pressure: 0.0211mmHg at 25°C
• Refractive Index: 1.673
• CAS DataBase Reference: N-(thiophen-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(thiophen-2-yl)benzamide(136-34-5)
• EPA Substance Registry System: N-(thiophen-2-yl)benzamide(136-34-5)

Safety Data

• Hazardous Substances Data: 136-34-5(Hazardous Substances Data)

Upstream product

• 609-40-5 2-nitrothiophene 
• 4110-75-2 (E)-(2-methoxyvinyl)benzene 
• 616-46-6 thiophen-2-ylamine 
• 98-88-4 benzoyl chloride 
• 3437-95-4 2-Iodothiophene 
• 100-47-0 benzonitrile 
• 613-94-5 benzoic acid hydrazide 
• 55-21-0 benzamide 

Downstream Products

• 100037-80-7 6-phenyl-thieno[2,3-b]pyridine 

Relevant articles and documents

Photochemistry of β-Methoxystyrene in the Presence of Nitroarenes. Unusual Products Formation

The irradiation of β-methoxystyrene in the presence of nitroarenes gave un unusual product deriving from dimerization and oxidation of the starting material.In the reaction mixture also an amide was identified.

Acidylation method of amine

The invention discloses an acidylation method of amine.The method includes the following steps that amine derivatives, hydrazide derivatives, organic peroxide and a catalyst are dissolved in a solvent and react at the temperature of 40-80 DEG C, and amide derivatives are obtained.The amide derivatives and hydrazide derivatives serve as initiators, the raw materials are easy to obtain and the number of varieties is large.Products obtained through the method are diverse in type, can be directly used and can also be used for other further reactions.The method is mild in reaction condition, simple in reaction operation and post-processing process, high in product yield and suitable for scale production.

An improved protocol for synthesis of N-arylamides and benzoxazoles by the copper-catalyzed reaction of aryl halides with nitriles

An improved protocol for the synthesis of N-arylamides and benzoxazoles by the copper-catalyzed reaction of aryl halides with nitriles has been developed. Use of acetaldoxime as the hydrolysis reagent instead of H2O facilitates the operation of the reaction. The significantly decreased amount of nitriles, along with use of weak base K2CO3 instead of strong base KOH, makes this transformation atom-efficient and environmentally benign. A variety of N-arylamides and benzoxazole derivatives can be synthesized according to this approach.