136-79-8

Basic information

• Product Name: 2-ETHOXY-5-NITROANILINE
• Synonyms: 2-ETHOXY-5-NITROANILINE;4-Nitro-2-aminophenetole;5-Nitro-o-phenetidine;Neo-Douxan
• CAS NO: 136-79-8
• Molecular Formula: C₈H₁₀N₂O₃
• Molecular Weight: 182.18
• Mol File: 136-79-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 96.5°C
• Boiling Point: 355.56°C (rough estimate)
• Flash Point: 170.5°C
• Appearance: /
• Density: 1.2477 (estimate)
• Vapor Pressure: 2.56E-05mmHg at 25°C
• Refractive Index: 1.6010 (estimate)
• PKA: 2.37±0.10(Predicted)
• CAS DataBase Reference: 2-ETHOXY-5-NITROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHOXY-5-NITROANILINE(136-79-8)
• EPA Substance Registry System: 2-ETHOXY-5-NITROANILINE(136-79-8)

Safety Data

• Hazardous Substances Data: 136-79-8(Hazardous Substances Data)

Usage

General Description

2-Ethoxy-5-nitroaniline is a chemical compound with the molecular formula C8H10N2O3. It is a yellow crystalline solid that is primarily used in the production of dyes and pigments. 2-Ethoxy-5-nitroaniline is also used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is considered to be a hazardous substance and precautions should be taken when handling and storing it. Additionally, it is important to follow safety guidelines and protocols when working with 2-ethoxy-5-nitroaniline to minimize the risk of exposure and potential health hazards.

InChI:InChI=1/C8H10N2O3/c1-2-13-8-4-3-6(10(11)12)5-7(8)9/h3-5H,2,9H2,1H3

Upstream product

• 610-54-8 2,4-dinitro-1-ethoxybenzene 
• 59263-63-7 2-ethoxy-5-nitro-benzamide 
• 94-70-2 ortho-phenitidine 
• 64-17-5 ethanol 
• 119-27-7 2,4-dinitroanisole 
• 581-08-8 2'-ethoxyacetanilide 
• 29669-41-8 2-ethoxy-5-nitrobenzonitrile 
• 7647-01-0 hydrogenchloride 
• 116496-77-6 acetic acid-(2-ethoxy-5-nitro-anilide) 
• 613-43-4 2,2'-diethoxyazobenzene 

Relevant articles and documents

Regioselective Reduction of Substituted Dinitroarenes Using Baker's Yeast

A range of substituted dinitroaromatic compounds have been reduced using baker's yeast (Saccharamyces cerevisiae), in some cases with very high selectivity.A model is presented to account for the origin of the selectivity together with a possible mechanism for the reduction.

PARTIAL REDUCTION OF DINITROARENES TO NITROANILINES WITH HYDRAZINE HYDRATE.

Dinitroarenes containing substituents such as hydroxyl and amine groups could be conveniently reduced with 3 molar equivalents of hydrazine hydrate in presence of Raney nickel catalyst in ethanol/1,2-dichloro-ethane solvent mixture to give a product wherein one of the two nitro groups was reduced to the amino group. The yields of the partial reduction products are good. Under similar conditions alkoxyl substitutes in the o,p-position to the nitro groups were displaced by the hydrazine to give 2,4-dinitrophenyl-hydrazine as the main product. The details of the reduction reaction are described.