610-54-8Relevant articles and documents
SNAr reactions of 1-halo-2,4-dinitrobenzenes with alkali-metal ethoxides: Differential stabilization of ground state and transition state determines alkali-metal ion catalysis or inhibition
Yang, Kiyull,Kim, Min-Young,Um, Ik-Hwan
, p. 1812 - 1818 (2015)
A kinetic study on SNAr reactions of 1-halo-2,4-dinitrobenzenes (6a-6d) with alkali-metal ethoxides (EtOM; M = Li, Na, K and 18-crown-6-ether-complexed K) is reported. The plots of pseudo-first-order rate constant (kobsd) vs. [EtOM]
Rationalising the effects of ionic liquids on a nucleophilic aromatic substitution reaction
Hawker, Rebecca R.,Wong, Michaela J.,Haines, Ronald S.,Harper, Jason B.
supporting information, p. 6433 - 6440 (2017/08/10)
The nucleophilic aromatic substitution reaction between 1-fluoro-2,4-dinitrobenzene and ethanol was examined in a series of ionic liquids across a range of mole fractions. Temperature-dependent kinetic analyses were undertaken to determine the activation parameters for this reaction at the highest mole fraction. As the mole fraction of ionic liquid was increased, the rate constant of the reaction also increased, however the microscopic origin of the rate enhancement was shown to be different between different ionic liquids and also between different solvent compositions. These results indicate a balance between microscopic interactions that result in the observed solvent effects and a qualitative method for analysing such interactions is introduced.
Novel Chloroimidazolium-Based Ionic Liquids: Synthesis, Characterisation and Behaviour as Solvents to Control Reaction Outcome
Hawker, Rebecca R.,Panchompoo, Janjira,Aldous, Leigh,Harper, Jason B.
, p. 574 - 583 (2016/07/06)
Novel ionic liquids containing chlorine atoms on the imidazolium cation were synthesised. The physicochemical properties of these ionic liquids were investigated extensively, including glass transition, melting and decomposition temperatures, density, vis