136029-20-4

Upstream product

• 67-56-1 methanol 
• 20194-18-7 sodium phenyl-methanolate 
• 136029-16-8 ((2-thiazolylcarbonyl)methyl)triphenylphosphonium bromide 
• 136033-56-2 (4R,5S,6R)-4,5,6,7-tetrahydroxy-4,5:6,7-di-O-isopropylidene-1-(2-thiazolyl)-2(E)-hepten-1-one 
• 136029-15-7 1-(thiazol-2-yl)-2-(triphenyl-λ ⁵-phosphanylidene)ethan-1-one 
• 3292-77-1 2-bromo-1-thiazol-2-yl-ethanone 
• 136029-19-1 (S)-3-Benzyloxy-3-((4R,5R,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-1-thiazol-2-yl-propan-1-one 

Relevant academic research and scientific papers

Installation of the pyruvate unit in glycidic aldehydes via a Wittig olefination-Michael addition sequence utilizing a thiazole-armed carbonyl ylid. A new stereoselective route to 3-deoxy-2-ulosonic acids and the total synthesis of DAH, KDN, and 4-epi-KDN

A method for the installation of the (2-thiazolylcarbonyl)methylene group, i.e. a masked pyruvate unit owing to the thiazole to formyl equivalence, in sugar-derived aldehydes has been developed. The strategy involves stereoselective carbon-carbon and carb

Stereoselective construction of polyhydroxyalkyl 2-thiazolyl ketones (thiazole ketones) from D-glyceraldehyde and D-arabinose acetonides by Wittig-Michael sequence. A route to D-gluco-KDO

The carbonylolefination of the title alkoxy aldehydes by 2-thiazolecarbonylmethylenetriphenylphosphorane affords the corresponding (E)-enones which undergo syn-diastereoselective (ds, 85-95%) 1,4-conjugate addition of benzyl oxide anion; acid-catalyzed me