1360537-73-0

Basic information

• Product Name: 2,4-difluoro-N-(2-hydroxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide
• Synonyms: 2,4-difluoro-N-(2-hydroxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide
• CAS NO: 1360537-73-0
• Molecular Weight: 491.478
• Mol File: 1360537-73-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4-difluoro-N-(2-hydroxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-difluoro-N-(2-hydroxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide(1360537-73-0)
• EPA Substance Registry System: 2,4-difluoro-N-(2-hydroxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide(1360537-73-0)

Safety Data

• Hazardous Substances Data: 1360537-73-0(Hazardous Substances Data)

Upstream product

• 187278-01-9 5-(((4-bromophenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 145369-94-4 6-bromo-3-quinolinecarboxylic acid-4-ol 
• 152684-30-5 5-bromo-2-methoxy-3-nitropyridine 
• 67443-38-3 5-bromo-2-chloro-3-nitropyridine 
• 1086063-18-4 6-bromo-4-(pyridazin-4-yl)quinoline 
• 1086063-46-8 N-(5-bromo-2-methoxypyridine-3-yl)-2,4-difluorobenzene sulfonyl chloride 
• 884495-39-0 5-bromo-2-(methyloxy)-3-pyridinamine 
• 1086062-75-0 6-bromo-4-chloroquinoline hydrochloride 
• 1086062-66-9 GS⁽²⁶⁴⁾K₂₁₅₈ 
• 927801-23-8 6-bromo-4-iodoquinoline 
• 65340-70-7 6-bromo-4-chloroquinoline 

Relevant articles and documents

[11C]GSK2126458 and [18F]GSK2126458, the first radiosynthesis of new potential PET agents for imaging of PI3K and mTOR in cancers

GSK2126458 is a highly potent inhibitor of phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) with low picomolar to subnanomolar activity. [11C]GSK2126458 and [18F]GSK212 6458, new potential PET agents for imaging of PI3K and mTOR in cancer, were first designed and synthesized in 40-50% and 20-30% decay corrected radiochemical yield, and 370-740 and 37-222 GBq/lmol specific activity at end of bombardment (EOB), respectively.