1360619-12-0

Basic information

• Product Name: tert-butyl (3aR,4R,6S,6aS)-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)-6-(3-ethenylphenyl)tetrahydro-2,2-dimethyl-3aH-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate
• Synonyms: tert-butyl (3aR,4R,6S,6aS)-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)-6-(3-ethenylphenyl)tetrahydro-2,2-dimethyl-3aH-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate
• CAS NO: 1360619-12-0
• Molecular Weight: 489.728
• Mol File: 1360619-12-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (3aR,4R,6S,6aS)-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)-6-(3-ethenylphenyl)tetrahydro-2,2-dimethyl-3aH-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (3aR,4R,6S,6aS)-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)-6-(3-ethenylphenyl)tetrahydro-2,2-dimethyl-3aH-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate(1360619-12-0)
• EPA Substance Registry System: tert-butyl (3aR,4R,6S,6aS)-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)-6-(3-ethenylphenyl)tetrahydro-2,2-dimethyl-3aH-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate(1360619-12-0)

Safety Data

• Hazardous Substances Data: 1360619-12-0(Hazardous Substances Data)

Upstream product

• 153172-31-7 (3aR,4R,6aS)-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)tetrahydro-2,2-dimethyl-3aH-[1,3]dioxolo[4,5-c]pyrrole 
• 105990-41-8 (2R,3R,4S)-2-hydroxymethylpyrrolidine-3,4-diol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1360619-11-9 (3aR,4R,6S,6aS)-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)-6-(3-ethenylphenyl)tetrahydro-2,2-dimethyl-3aH-[1,3]dioxolo[4,5-c]pyrrole 
• 117859-48-0 C₈H₁₅NO₃ 

Downstream Products

• 1360619-08-4 (2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-{3-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]phenyl}prop-2-enamide hydrochloride 
• 1360619-13-1 tert-butyl (3aR,4R,6S,6aS)-4-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)tetrahydro-6-{3-[(1E)-3-methoxy-3-oxoprop-1-en-1-yl]phenyl}-2,2-dimethyl-5H-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate 

Relevant articles and documents

Synthesis of a C-iminoribofuranoside analog of the nicotinamide phosphoribosyltransferase (NAMPT) inhibitor FK866

FK866 (also named APO866 or WK175) is a potent NAMPT inhibitor being evaluated (Phase II) as a potential anticancer drug. The preparation of the C-iminoribofuranoside analog (2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-{3- [(2S,3S,4R,5R)-3,4-dihydroxy-5-(h