1360624-40-3

Upstream product

• 1242269-31-3 ethyl 5-amino-2-(2,2-difluoroethoxy)-4-(methylamino)benzoate 
• 1360624-07-2 N-(3-nitro-2,4-dichloro-benzyl)-2,2-dimethyl-propionamide 
• 1360624-05-0 3-nitro-2,4-dichloro-benzylamine 
• 1360624-03-8 N-(3-nitro-2,4-dichloro-benzyl)-2,2,2-trifluoroacetamide 
• 1360623-99-9 N-(3-amino-2,4-dichloro-benzyl)-2,2-dimethyl-propionamide 
• 1360623-95-5 3-amino-2,4-dichloro-benzamide 
• 50917-27-6 3-acetamido-2,4-dichlorobenzoic acid 
• 1242269-30-2 ethyl 2-(2,2-difluoroethoxy)-4-(methylamino)-5-nitrobenzoate 
• 1360624-01-6 N-(2,4-dichloro-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide 
• 1219119-52-4 2-fluoro-4-methylamino-5-nitro-benzoic acid ethyl ester 
• 601-88-7 2,6-dichloronitrobenzene 
• 179011-37-1 SRS₁₄-41 

Downstream Products

• 1360624-51-6 2-{2,6-dichloro-3-[(2,2-dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoro-ethoxy)-1-methyl-1H-benzimidazole-5-carboxylic acid 
• 1360622-16-7 N-(3-cyano-phenyl)-2-{2,6-dichloro-3-[(2,2-dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoro-ethoxy)-1-methyl-1H-benzimidazole-5-carboxylic acid amide 
• 1360622-17-8 N-(2,4-dichloro-phenyl)-2-{2,6-dichloro-3-[(2,2-dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoro-ethoxy)-1-methyl-1H-benzimidazole-5-carboxylic acid amide 
• 1360622-07-6 N-(4-bromo-phenyl)-2-{2,6-dichloro-3-[(2,2-dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoro-ethoxy)-1-methyl-1H-benzimidazole-5-carboxylic acid amide 

Relevant academic research and scientific papers

NEW COMPOUNDS

This invention relates to compounds of formula (I) their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions. A, M, W, R1, R2, R6, R7, R8 have meanings given in the description.

NEW COMPOUNDS

This invention relates to compounds of formula I their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions. A, M, W, R1, R2, R6, R7, R8 have meanings given in the description.