136116-42-2

Basic information

• Product Name: Silane, (1,1-dimethylethyl)dimethyl(1-phenylpropoxy)-
• Synonyms: Silane, (1,1-dimethylethyl)dimethyl(1-phenylpropoxy)-
• CAS NO: 136116-42-2
• Molecular Formula: C₁₅H₂₆OSi
• Molecular Weight: 250.45
• Mol File: 136116-42-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Silane, (1,1-dimethylethyl)dimethyl(1-phenylpropoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1,1-dimethylethyl)dimethyl(1-phenylpropoxy)-(136116-42-2)
• EPA Substance Registry System: Silane, (1,1-dimethylethyl)dimethyl(1-phenylpropoxy)-(136116-42-2)

Safety Data

• Hazardous Substances Data: 136116-42-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 138983-08-1 Dichlor<(1,1-dimethylethyl)dimethylsilyl>methan 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 93-54-9 1-Phenyl-1-propanol 
• 54925-64-3 N-(tert-butyldimethylsilyl)imidazole 
• 148259-45-4 1-(tert-butyldimethylsiloxy)-2,2-dichloro-1-phenylpropane 

Downstream Products

• 93-55-0 1-phenyl-propan-1-one 
• 93-54-9 1-Phenyl-1-propanol 

Relevant articles and documents

tert-Butyldimethylsilyldihalomethyllithium as a dihalomethylene dianion synthon. 1,3-Rearrangement and 1,4-rearrangement of silyl group from carbon to oxide

One-pot synthesis of R1CH(OSiMe2-t-Bu)CX2CH(OH)R2 (X = Cl, Br) by successive addition of two different aldehydes (R1CHO and R2CHO) has been achieved starting from tert-butyldimethylsilyldihalomethyllithium. Treatment of a THF solution of the title carbanion (X = Cl) with p-MeOC6H4CHO or n-BuCHO followed by an addition of HMPA and benzaldehyde gave the corresponding 1,3-diol monosilyl ether in 83% or 45% yield, respectively. The use of oxirane in place of aldehyde as the first electrophile followed by addition of benzaldehyde provided 1,4-diol monosilyl ether.

Efficient and chemoselective protection of alcohols and phenols with tert-butyldimethylchlorosilane (TBDMCS) under solvent-free conditions

Various types of primary and secondary alcohols and phenols can be converted efficiently to their corresponding TBDMS ethers using TBDMCS/imidazole under solvent-free conditions. Elimination of DMF, accompanied with an easy non-aqueous work-up and a high rate enhancement of the reaction are worthy to be mentioned for the presented method. The reactions show absolute chemoselectivity for the protection of primary in the presence of secondary alcohols.