Welcome to LookChem.com Sign In|Join Free

CAS

  • or

13620-47-8

Post Buying Request

13620-47-8 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

13620-47-8 Usage

General Description

1-(2-chloroacetyl)-3-(4-chlorophenyl)urea is a chemical compound with the molecular formula C10H10Cl2N2O2. It is a derivative of urea and contains both chloroacetyl and chlorophenyl groups. 1-(2-chloroacetyl)-3-(4-chlorophenyl)urea is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has been studied for its potential use as an insecticide and fungicide due to its pesticidal activity. Additionally, it has been investigated for its potential use in the treatment of various diseases, including cancer and diabetes. Its unique chemical structure and functional groups make it a versatile and valuable building block for the synthesis of a wide range of biologically active compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 13620-47-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,6,2 and 0 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13620-47:
(7*1)+(6*3)+(5*6)+(4*2)+(3*0)+(2*4)+(1*7)=78
78 % 10 = 8
So 13620-47-8 is a valid CAS Registry Number.

13620-47-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-N-[(4-chlorophenyl)carbamoyl]acetamide

1.2 Other means of identification

Product number -
Other names 1-chloroacetyl-3-(4-chloro-phenyl)-urea

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13620-47-8 SDS

13620-47-8Relevant articles and documents

Design, Synthesis, and Antitumor Activity Evaluation of Trifluoromethyl-Substituted Pyrimidine Derivatives Containing Urea Moiety

Chao, Gao,Heyi, Yan,Honglin, Dai,Hongmin, Liu,Jiaxin, Zheng,Lihong, Shan,Limin, Liu,Luye, Zhang,Na, Li,Qiurong, Zhang,Tao, Wang,Xiujuan, Liu,Yang, Zhang,Zhengjie, Wang

, p. 1301 - 1311 (2021/12/23)

Abstract: In order to find efficient new antitumor drugs, a series of novel pyrimidine derivatives containing urea moiety were designed and synthesized, and the antitumor activity of four human tumor cells was evaluated by MTT analysis. The results showed that most of the target compounds exhibited moderate antitumor activity. In particular, the IC50 (concentration required to achieve 50% inhibition of the tumor cell proliferation) value of compound 2-((4-(4-ethylphenoxy)-6-(trifluoromethyl)pyrimidin-2-yl)thio)-N-((4-ethylphenyl)carba-moyl)acetamide for MGC-803 (human gastric carcinoma cell line) was 2.51 ± 0.17 μmol L–1, the anti-proliferative activity was significantly better than the positive control drug 5-fluorouracil. Molecular docking revealed that this compound can bind well to the active site of epidermal growth factor receptor (EGFR), and it may become a potential antitumor drug.

N-Acylureas and their behavior against amines

Schweim

, p. 814 - 825 (2007/10/02)

-

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 13620-47-8