1363382-27-7Relevant academic research and scientific papers
The acylated piperazine compound and use thereof
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Paragraph 0167; 0296; 0306-0308, (2019/05/16)
The present invention relates to acylated piperazine compound and its use, further relates to the pharmaceutical composition. The compound of the invention or the pharmaceutical composition can be used as dipeptidyl peptidase - IV (DPP - IV) inhibitors.
Synthesis of Substituted Cyclopropanecarboxylates via Room Temperature Palladium-Catalyzed α-Arylation of Reformatsky Reagents
Greszler, Stephen N.,Halvorsen, Geoff T.,Voight, Eric A.
, p. 2490 - 2493 (2017/05/24)
The room temperature palladium-catalyzed cross-coupling of aromatic and heteroaromatic halides with Reformatsky reagents derived from 1-bromocyclopropanecarboxylates provides an exceptionally mild method for enolate α-arylation. The method is tolerant of a wide range of functionalities and dramatically shortens many of the existing routes to access widely used 1,1-disubstituted cyclopropanecarboxylate derivatives.
