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56423-63-3

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56423-63-3 Usage

General Description

2-Bromopyrazine is a chemical compound with the molecular formula C4H3BrN2. It is a colorless to pale yellow liquid that is used in the synthesis of pharmaceuticals and agrochemicals. 2-Bromopyrazine is a versatile building block in organic chemistry, often used as a substrate in the preparation of various heterocyclic compounds. It has also been found to possess biological activities, such as antiproliferative and antitumor properties. Additionally, 2-Bromopyrazine is commonly used as a flavor and fragrance ingredient due to its distinctive odor. Overall, it is an important and versatile chemical with various industrial and research applications.

Check Digit Verification of cas no

The CAS Registry Mumber 56423-63-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,4,2 and 3 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 56423-63:
(7*5)+(6*6)+(5*4)+(4*2)+(3*3)+(2*6)+(1*3)=123
123 % 10 = 3
So 56423-63-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H3BrN2/c5-4-3-6-1-2-7-4/h1-3H

56423-63-3 Well-known Company Product Price

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  • Aldrich

  • (CDS005022)  2-Bromopyrazine  AldrichCPR

  • 56423-63-3

  • CDS005022-100MG

  • 644.67CNY

  • Detail
  • Aldrich

  • (754595)  2-Bromopyrazine  97%

  • 56423-63-3

  • 754595-1G

  • 1,268.28CNY

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56423-63-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Bromopyrazine

1.2 Other means of identification

Product number -
Other names 2-bromopyrazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:56423-63-3 SDS

56423-63-3Relevant articles and documents

Synthesis and Characterization of 2-(2-Pyridinyl)pyrazine and 2,2′-Bipyrazine Derivatives

KomReddy, Venugopal,Rillema, D. Paul,Nguyen, Huy,Kadel, Lava

, p. 972 - 979 (2019/02/05)

A convenient and high yield preparation of derivatives of 2-(2-pyridinyl)pyrazine and derivatives of 2,2′-bipyrazine compounds from their derivatives of bromopyrazine using Stille coupling is reported. X-ray structures, elemental analyses, 1H, 13C-NMR, and mass spectral data of the compounds are given.

Metalation of bromodiazines. Diazines XL

Decrane, Laurence,Pie, Nelly,Turck, Alain

, p. 509 - 513 (2007/10/03)

The syntheses of 2-bromopyrazine, 2,4-dibromopyrimidines, and 3-bromo-6-phenylpyrazine were improved and their metalation with lithium alkylamides was studied.

Silyl-mediated halogen/halogen displacement in pyridines and other heterocycles

Schlosser, Manfred,Cottet, Fabrice

, p. 4181 - 4184 (2007/10/03)

Heating with bromotrimethylsilane converts 2-chloropyridine into 2-bromopyridine and 2-chloro-6-methylpyridine into 2-bromo-6-methylpyridine. Both 2-chloropyridines and 2-bromopyridines give the corresponding iodo compound when treated with in situ generated iodotrimethylsilane. Although 3- and 4-chloropyridine are completely inert, 2,4-dichloropyridine undergoes the halogen/halogen exchange simultaneously at the 2- and 4-position. Halogen displacement takes place exclusively at the 2-position with 2,3-dichloropyridine and 2,5-dichloropyridine. In agreement with the intermediacy of N-trimethylsilylpyridinium salts as a prerequisite for the occurrence of halogen exchange, neither 2-fluoropyridine and 2-fluoro-6-methylpyridine nor any 2,6-dihalopyridine reacts. Finally, bromine/chlorine and iodine/chlorine substitution can also be accomplished with 2-or 4-chloroquinoline, 1-chloroisoquinoline, 2-chloropyrimidine, chloropyrazine and 2,3-dichloroquinoxaline as substrates. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2002).

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