1363411-36-2Relevant academic research and scientific papers
Controllable regioselective construction of both functional α-methylene-β- and -γ-amino acid derivatives through an organocatalyzed tandem allylic alkylation and amination
Pan, Feng,Chen, Jian-Ming,Qin, Tian-You,Zhang, Sean Xiao-An,Liao, Wei-Wei
, p. 5324 - 5334 (2012/10/29)
A new controllable and regioselective allylic alkylation and amination reaction has been developed for the highly selective construction of compounds containing α-alkylidene-β-amino acid and α-methylene-γ- butyrolactam moieties. Furthermore, on the basis of this controllable strategy, multicomponent tandem reactions have also been accomplished. The subsequent transformations of the densely functionalized products have readily afforded a range of useful building blocks, which have potential utility in organic synthesis. Copyright
Construction of highly functional α-amino nitriles via a novel multicomponent tandem organocatalytic reaction: A facile access to α-methylene γ-lactams
Pan, Feng,Chen, Jian-Ming,Zhuang, Zhe,Fang, Yin-Zhi,Zhang, Sean Xiao-An,Liao, Wei-Wei
, p. 2214 - 2217 (2012/04/10)
The first tertiary amine-catalyzed multicomponent tandem Strecker-allylic-alkylation (SAA) reaction has been developed, which provides a facile access to functionalized α-amino nitriles, which could be readily converted into α-methylene-γ-butyrolactams. The Royal Society of Chemistry 2012.
