1364369-10-7Relevant articles and documents
A FRET-based probe with a chemically deactivatable quencher
Leriche, Geoffray,Budin, Ghyslain,Darwich, Zeinab,Weltin, Denis,Mely, Yves,Klymchenko, Andrey S.,Wagner, Alain
, p. 3224 - 3226 (2012/05/20)
A new concept of a chemically deactivatable quencher is proposed for a FRET-based probe that turns-on its fluorescence by either an enzymatic cleavage or a chemical reagent (sodium dithionite). This concept allowed us to quantify the caspase-3 cleavage activity in solution and to reveal unreacted probes in cell experiments. The Royal Society of Chemistry 2012.