1364684-91-2Relevant academic research and scientific papers
Solvent-free one-pot synthesis of sulfonephthaleins from saccharin and phenols
Tillu,Dumbre,Borate,Wakharkar,Choudhary
, p. 1101 - 1107 (2012)
Sulfonephthaleins can be synthesized in a single pot from saccharin and phenol via the in situ formation of 2-sulfobenzoic anhydride, followed by its reaction with phenol using H2SO4 as the condensing agent, in the absence of any solvent. This solvent-free synthesis is more economical and environmentally benign. Copyright Taylor & Francis Group, LLC.
