Synthetic Communications p. 1101 - 1107 (2012)
Update date:2022-07-30
Topics:
Tillu
Dumbre
Borate
Wakharkar
Choudhary
Sulfonephthaleins can be synthesized in a single pot from saccharin and phenol via the in situ formation of 2-sulfobenzoic anhydride, followed by its reaction with phenol using H2SO4 as the condensing agent, in the absence of any solvent. This solvent-free synthesis is more economical and environmentally benign. Copyright Taylor & Francis Group, LLC.
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