136744-84-8

Basic information

• Product Name: (E)-methyl 3-N-methylacetamido-3-phenyl-2-propenoate
• Synonyms: (E)-methyl 3-N-methylacetamido-3-phenyl-2-propenoate
• CAS NO: 136744-84-8
• Molecular Weight: 233.267
• Mol File: 136744-84-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-methyl 3-N-methylacetamido-3-phenyl-2-propenoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-methyl 3-N-methylacetamido-3-phenyl-2-propenoate(136744-84-8)
• EPA Substance Registry System: (E)-methyl 3-N-methylacetamido-3-phenyl-2-propenoate(136744-84-8)

Safety Data

• Hazardous Substances Data: 136744-84-8(Hazardous Substances Data)

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 136744-88-2 (E)-methyl 3-acetamido-3-phenyl-2-propenoate 
• 74-88-4 methyl iodide 
• 72569-96-1 methyl (Z)-3-acetylamino-3-phenylacrylate 
• 614-27-7 methyl 3-oxo-3-phenylpropionate 
• 70272-01-4 methyl 3-amino-3-phenylacrylate 

Downstream Products

• 136744-90-6 (R)-(+)-methyl 3-N-methylacetamido-3-phenylpropanoate 
• 136744-90-6 (S)-3-(Acetyl-methyl-amino)-3-phenyl-propionic acid methyl ester 
• 136744-96-2 (R)-3-N-methylacetamido-3-phenyl-1-propanol 
• 136744-95-1 (R)-3-methylamino-3-phenyl-1-propanol 
• 136744-90-6 methyl 3-N-methylacetamido-3-phenylpropanoate 
• 136744-83-7 (Z)-methyl 3-N-methylacetamido-3-phenyl-2-propenoate 

Relevant articles and documents

Enantioselective synthesis of β-amino acids based on BINAP-ruthenium(II) catalyzed hydrogenation

BINAP-Ru(II) catalyzed hydrogenation of β-substituted (E)-β-(acylamino)acrylic acids allows efficient enantioselective synthesis of β-amino acids. The Z double bond isomers which possess an intramolecular hydrogen bond between amide and ester groups are more reactive but are hydrogenated with poor enantioselectivity. BINAP-Rh(I) complexes afford only moderate stereoselectivity with the opposite sense of enantioselection.