136759-41-6 Usage
General Description
The chemical (S)-6-Methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid, also known as (S)-6-Methoxy-2-naphthoic acid, is a compound with a molecular formula of C13H14O3. It is a derivative of naphthalene, an aromatic hydrocarbon, and is primarily used in the pharmaceutical industry in the synthesis of various drugs, such as antipsychotic and antifungal medications. (S)-6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALENE-2-CARBOXYLIC ACID is known for its ability to inhibit the enzyme squalene epoxidase, which is involved in the biosynthesis of ergosterol, an essential component of fungal cell membranes. As a result, (S)-6-Methoxy-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid has potential applications in the treatment of fungal infections. Additionally, it has been studied for its potential anti-inflammatory and antioxidant properties, making it a subject of interest in drug development and research.
Check Digit Verification of cas no
The CAS Registry Mumber 136759-41-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,7,5 and 9 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 136759-41:
(8*1)+(7*3)+(6*6)+(5*7)+(4*5)+(3*9)+(2*4)+(1*1)=156
156 % 10 = 6
So 136759-41-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H14O3/c1-15-11-5-4-8-6-10(12(13)14)3-2-9(8)7-11/h4-5,7,10H,2-3,6H2,1H3,(H,13,14)/t10-/m0/s1
136759-41-6Relevant articles and documents
Microbial Reduction of 1-Tetralone 2-Carboxyesters as a Source of New Asymmetric Synthons
Buisson, Didier,Cecchi, Roberto,Laffitte, Jean-Alex,Guzzi, Umberto,Azerad, Robert
, p. 3091 - 3094 (1994)
The reduction of unsubstituted or methoxy-substituted (+/-)-2-carboxyethyl-1-tetralones by selected microorganisms affords optically active 1-hydroxy-2-carboxyethyl tetralins which can be used as versatile asymmetric synthons, for example in the preparation of biologically active methoxy-substituted 2R-aminotetralins. 1R,2R-(cis)-hydroxyesters of high optical purity are obtained with yeast strains, while the use of filamentous fungi leads to the enantiomeric 1S,2S-(cis)-hydroxyesters.
Kappa opioid receptor ligands
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Page/Page column 7, (2008/06/13)
Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid
