136804-01-8Relevant academic research and scientific papers
A practical synthesis of N1-methyl-2'-deoxy-ψ-uridine (ψ-thymidine) and its incorporation into G-rich triple helix forming oligonucleotides
Bhattacharya,Devivar,Revankar
, p. 1269 - 1287 (1995)
A convenient synthesis of N1-methyl-2'-deoxy-ψ-uridine (ψ-thymidine, ψT, 7a) has been accomplished in good yield. The structural conformation of 7a was derived by 2D NMR and 1D NOE experiments. The nucleoside 7a has been incorporated into G-rich triplex f
Aminopyridinyl–Pseudodeoxycytidine Derivatives Selectively Stabilize Antiparallel Triplex DNA with Multiple CG Inversion Sites
Okamura, Hidenori,Taniguchi, Yosuke,Sasaki, Shigeki
, p. 12445 - 12449 (2016)
The sequence-specific formation of triplex DNA offers a potential basis for genome-targeting technologies. In an antiparallel triplex DNA, the sequence-specificity is established by the formation of specific base triplets (G?GC, A?AT, and T?AT) between a
