136962-42-0

Basic information

• Product Name: ethyl 2-hydroxy-2-phenylphenylpropanoate
• CAS NO: 136962-42-0
• Molecular Weight: 270.328
• Mol File: 136962-42-0.mol

Chemical Properties

• CAS DataBase Reference: ethyl 2-hydroxy-2-phenylphenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-hydroxy-2-phenylphenylpropanoate(136962-42-0)
• EPA Substance Registry System: ethyl 2-hydroxy-2-phenylphenylpropanoate(136962-42-0)

Safety Data

• Hazardous Substances Data: 136962-42-0(Hazardous Substances Data)

Upstream product

• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 1589-82-8 phenylmagnesium bromide 
• 100-39-0 benzyl bromide 
• 774-40-3 hydroxy-phenyl-acetic acid ethyl ester 
• 87100-28-5 pinacol benzylboronate 
• 6337-34-4 2,2-dimethyl-5-phenyl-1,3-dioxolan-4-one 
• 64-17-5 ethanol 
• 136962-24-8 5-benzyl-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-one 
• 93406-83-8 3-amino-2,2-diphenyl-propionic acid ethyl ester; hydrochloride 

Downstream Products

• 20978-75-0 2-Carbamoylmethoxy-2,3-diphenyl-propionamide 
• 451-40-1 phenyl benzyl ketone 

Relevant articles and documents

Nucleophilic addition of benzylboronates to activated ketones

A method has been developed for the addition of benzylboronic acid pinacol ester to activated ketones including trifluoromethyl ketones in good yields. The use of DABCO as an additive was found to enhance the rate and efficiency of this reaction. In react

Ethyl Mandelate as a Convenient New Benzoyl Anion Equivalent

Ethyl mandelate acts as a convenient benzoyl anion equivalent for the formation of alkyl aryl ketones by deprotonation-alkylation followed by flash vacuum pyrolysis.

PLE catalyzed hydrolyses of α-substituted α-hydroxy esters: The influence of the substituents

The enzymatic hydrolyses of a variety of α-substituted mandelic and lactic esters using pig liver esterase (PLE) have been investigated. High to moderate enantioselectivity was found for various α-substituted mandelic esters, whereas PLE showed low to no enantioselectivity for α-substituted lactic esters. We observed that the enantioselectivity of PLE depends strongly on the length and nature of the substituent at the α-position. Some sequences for an active site model of PLE are discussed.