1369807-40-8Relevant articles and documents
Preparation method of (4-isopropoxy-2-methyl)phenyl isopropyl ketone
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Paragraph 0042; 0045; 0052; 0055, (2020/08/27)
The invention relates to a preparation method of (4-isopropoxy-2-methyl)phenyl isopropyl ketone. The preparation method specifically comprises the following steps: reacting m-cresol with thiocyanate under the action of a catalyst to obtain a product A; reacting the product A with halogenated isopropane under the action of an alkali and a catalyst to obtain a product B; carrying out a reaction on the product B and isopropyl magnesium halide, and carrying out a treatment to obtain the (4-isopropoxy-2-methyl)phenyl isopropyl ketone. The purity of prepared (4-isopropoxy-2-methyl)phenyl isopropyl ketone is 99% or above, and the total yield is 79% or above. According to the method, the use of toxic reagents and generation of a large amount of acid wastewater are avoided, the reaction temperatureis reduced, the reaction yield is increased, the process route is simple and efficient, the cost is reduced, the purity of the obtained product is high, the production safety is greatly improved, andindustrial popularization is facilitated.
COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES
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Paragraph 00616-00618, (2019/03/12)
The present disclosure relates to compounds according to Formula (I), useful for treating diseases.
