137-41-7

Basic information

• Product Name: Potassium N-methyldithiocarbamate
• Synonyms: potassium methyldithiocarbamate;Potassium N-methyldithiocarbamate;wemcide cw 104;CARBAMOTHIOIC ACID METHYL MONOPOTASIUM SALT;n-methyldithio-carbamicacipotassiumsalt;metampotassium;Carbamodithioic acid, methyl-, monopotassium salt;potassium n-methyldithio carbamat
• CAS NO: 137-41-7
• Molecular Formula: C₂H₄NS₂*K
• Molecular Weight: 145.29
• EINECS: 205-292-5
• Mol File: 137-41-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 120.3 °C at 760 mmHg
• Flash Point: 26.6 °C
• Appearance: crystalline solid, but often supplied as a brown or yellow aqueous solution
• Density: 1.199 g/cm³
• Vapor Pressure: 15.3mmHg at 25°C
• Stability: Stable, but decomposes in water solution to give toxic hydrogen sulfide. Incompatible with water, acids, copper, zinc.
• CAS DataBase Reference: Potassium N-methyldithiocarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: Potassium N-methyldithiocarbamate(137-41-7)
• EPA Substance Registry System: Potassium N-methyldithiocarbamate(137-41-7)

Safety Data

• RIDADR: 2588
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 137-41-7(Hazardous Substances Data)

Usage

Chemical Properties

crystalline solid, but often supplied as a brown or yellow aqueous solution

Uses

Potassiummethyldithiocarbamate is a herbicide.

General Description

A concentrated aqueous solution. Clear orange liquid with a pungent rotten-egg odor.

Air & Water Reactions

Slowly decomposes generating carbon disulfide and methylamine. Addition of water increases the rate of decomposition.

Reactivity Profile

Potassium N-methyldithiocarbamate slowly decomposes in water to give hydrogen sulfide and methylamine. Dilution increases the rate of decomposition. Acidification increases the rate of decomposition. Reactions with aldehydes, nitrides, and hydrides generate flammable gases. Incompatible with acids, peroxides, and acid halides.

InChI:InChI=1/C2H5NS2.K/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1

Upstream product

• 75-15-0 carbon disulfide 
• 74-89-5 methylamine 
• 624-92-0 Dimethyldisulphide 
• 63-25-2 1-naphthalenol methylcarbamate 

Downstream Products

• 556-61-6 methyl thioisocyanate 
• 129880-94-0 6-[2-(4-Hydroxy-phenyl)-2-(5-methyl-6-thioxo-[1,3,5]thiadiazinan-3-yl)-acetylamino]-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 2438-90-6 N,N'-dimethylthioperoxydicarbamic acid 
• 10048-06-3 p-Tolyl-N-methyl-trithiopercarbamat 
• 131602-28-3 7-<2-(Dihydro-5-methyl-6-thioxo-2H-1,3,5-thiadiazine-3<4H>-yl)-2-phenyl>acetamido-3-methyl-3-cephem-4-carboxylic acid 
• 41126-61-8 4-hydroxy-3-methyl-4-phenyl-2-thioxo-thiazolidine-5-carboxylic acid ethyl ester 

Relevant articles and documents

Extractive spectrophotometric method for the determination of carbaryl in environmental samples

In the view of the potential hazards associated with the widespread use of carbaryl insecticide, a new simple extractive spectrophotometric method has been developed for its determination in environmental samples viz. soil, water and foodstuffs for its safer and more effective use. The proposed method is based on the microwave assisted alkaline hydrolysis of the insecticide to methylamine. The later is measured as methyl isobutyl ketone (MIBK) extractable yellow nickel(II)-methyldithiocarbamate complex at 380 nm through the reaction with carbon disulfide and nickel(II) acetate. The insecticide can be determined in the linearity range from 2.01 to 60.3 μg mL-1 with a correlation coefficient of 0.996. The method has been applied to the analysis of carbaryl in its commercial formulation and its recovery from vegetable and water samples for monitoring health hazards. Recoveries of the insecticide from vegetables and spiked water samples were good, ranging from 87.6-92.8%, with RSDs ranging from 0.54-1.02%. The method has also been validated for investigating the sorption of carbaryl on five soils with different characteristics to evaluate its leaching behaviour which is a measure of ground and surface water contamination. The leaching potential of the insecticide in terms of groundwater ubiquity score (GUS) has values in the range 1.8-2.2 classifying it as transition leacher hence it has potential to contaminate groundwater.

Tetrahydro-2H-1,3,5-thiadiazine-5-(4-pyridylcarboxamide)-2-thione derivatives as prodrugs for isoniazid; synthesis, investigations and in vitro antituberculous activity.

3-Substituted-5-(4-pyridylcarboxamido)tetrahydro-2H-1,3,5-thiad iazine-2- thione derivatives 5a-e were synthesized as prodrugs for isoniazid (INH) to overcome the resistance developed with its therapeutic use. These prodrugs revealed higher lipophilicity compared with INH. Their degradation kinetics were studied in vitro using aqueous buffer solutions of pH values 1.2 and 7.4 was well as biological media of human plasma and rat liver homogenate at 37 degrees C. They were more stable toward enzymatic degradation in biological than in chemical media. Release of INH from these derivatives was detected as a result of both chemical and enzymatic hydrolysis by HPLC. The antimycobacterial activity of the synthesized compounds and INH was tested in vitro against human type of Mycobacterium tuberculosis. They exhibited a greater antitubercular activity than the parent drug. This result is considered as an indicator for an improved permeation of the synthesized prodrugs through mycobacterial cell membranes relative to INH.

Synthesis and antimicrobial activities of some new tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives of ampicillin

-