1370651-36-7

Basic information

• Product Name: 6-[bis(tert-butoxycarbonyl)amino]-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridazine-3-carboxylic acid
• Synonyms: 6-[bis(tert-butoxycarbonyl)amino]-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridazine-3-carboxylic acid
• CAS NO: 1370651-36-7
• Molecular Weight: 546.38
• Mol File: 1370651-36-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-[bis(tert-butoxycarbonyl)amino]-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridazine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[bis(tert-butoxycarbonyl)amino]-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridazine-3-carboxylic acid(1370651-36-7)
• EPA Substance Registry System: 6-[bis(tert-butoxycarbonyl)amino]-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridazine-3-carboxylic acid(1370651-36-7)

Safety Data

• Hazardous Substances Data: 1370651-36-7(Hazardous Substances Data)

Upstream product

• 1370651-34-5 C₂₅H₃₀Cl₂FN₃O₇ 
• 1370651-32-3 C₂₂H₂₅Cl₃FN₃O₅ 
• 1370651-29-8 C₁₂H₉Cl₃FN₃O 
• 330156-50-8 (R)-1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol 
• 290835-85-7 2',6'-dichloro-3'-fluoroacetophenone 
• 756520-66-8 1-(2,6-dichloro-3-fluorophenyl)ethanol 

Downstream Products

• 1370652-56-4 {5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-aminopyridazin-3-yl}-N-(1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)carboxamide 
• 1370651-40-3 C₃₅H₃₄Cl₂FN₅O₇ 
• 1201916-93-9 C₃₀H₃₄Cl₂FN₅O₇ 
• 1365267-27-1 6-amino-5-[(1{R})-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-{N}-[4-[(3{R},5{S})-3,5-dimethylpiperazine-1-carbonyl]phenyl]pyridazine-3-carboxamide 
• 1370651-02-7 {5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-aminopyridazin-3-yl}-N-[4-(4-pyridylcarbonyl)phenyl]carboxamide 

Relevant articles and documents

CRYSTALLINE FORM OF COMPOUND SUPPRESSING PROTEIN KINASE ACTIVITY, AND APPLICATION THEREOF

Provided are a compound as represented by structural formula (I) ({5 -[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-aminopyridazin-3-yl}-N-{4-[((3S,5R)-3,5-di methylpiperazinyl)carbonyl]phenyl}carboxamide hydrochloride) and a novel crystalline form of a

SUBSTITUTED PYRIDAZINE CARBOXAMIDE COMPOUNDS

The new pyridazine derivatives have unexpected drug properties as inhibitors of protein kinases especially against ALK and are useful in treating disorders related to abnormal protein kinase activities such as cancer, neurological and psychiatric diseases