137196-48-6

Upstream product

• 110927-06-5 8-methoxy-3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran 
• 109164-01-4 N,N-di-n-propyl-8-methoxy-3-chromanamine hydrochloride 
• 110927-06-5 (+)-8-methoxy-3,4-dihydro-3-(di-n-propylamino)-2H-1-benzylpyran 
• 110927-06-5 (-)-8-methoxy-3,4-dihydro-3-(di-n-propylamino)-2H-1-benzylpyran 
• 119755-78-1 (-)-8-methoxy-3,4-dihydro-3-diallylamino-2H-1-benzopyran 
• 119755-78-1 8-methoxy-3,4-dihydro-3-diallylamino-2H-1-benzopyran 
• 137279-47-1 8-methoxy-3,4-dihydro-3-nitro-2H-1-benzopyran 
• 112904-73-1 8-methoxychroman-3-amine 
• 92210-59-8 8-methoxy-3-nitro-2H-1-benzopyran 
• 119755-78-1 (+)-8-methoxy-3,4-dihydro-3-diallylamino-2H-1-benzopyran 

Relevant academic research and scientific papers

Methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyrans: New synthesis and dopaminergic activity

The synthesis of methoxy and hydroxy derivatives of 3,4-dihydro-3-(di-n-propylamino)-2H-1-benzopyran from readily available or commercial o-hydroxybenzaldehydes is described in six steps. The enantiomers of 8-hydroxy-3,4-dihydro-3-(di-n-propyl-amino)-2H-1-benzopyran 1b have been resolved. It is shown that the compound (-)-1b is a mroe selective D-2 agonist, compared to apomorphine.

Synthesis and dopaminergic activity of a new oxygen isostere of the 2-aminotetralins: N,N-dipropyl-8-hydroxy-3-chromanamine

The synthesis of N,N-dipropyl-8-hydroxy-3-chromanamine from 8-methoxy-4-chromanone oxime in seven steps is described.This compound is an oxygen isostere of the dopamine (DA) receptor agonist N,N-dipropyl-5-hydroxy-2-aminotetralin.In in vitro and in vivo t