13721-20-5 Usage
Description
3-Chloro-4-methoxyphenylacetic acid is a chemical compound characterized by the molecular formula C9H9ClO3. It is a white crystalline solid that exhibits solubility in organic solvents. 3-chloro-4-methoxyphenylacetic acid is a derivative of phenylacetic acid, distinguished by the presence of a chlorine atom and a methoxy group on the phenyl ring. Recognized for its potential as an intermediate in the preparation of various bioactive compounds, 3-chloro-4-methoxyphenylacetic acid also serves as a valuable building block in organic synthesis. Its unique chemical properties and reactivity position it as a significant reagent within the domain of organic chemistry.
Uses
Used in Pharmaceutical Synthesis:
3-Chloro-4-methoxyphenylacetic acid is utilized as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of new drugs with diverse therapeutic applications. Its unique structural features and reactivity facilitate the creation of a wide range of bioactive compounds, enhancing the discovery and innovation of novel medications.
Used in Agrochemical Production:
In the agrochemical industry, 3-chloro-4-methoxyphenylacetic acid is employed as a crucial building block for the production of various agrochemicals. Its incorporation into these compounds aids in the development of effective pesticides, herbicides, and other agricultural chemicals, supporting crop protection and yield enhancement.
Used in Organic Synthesis:
3-Chloro-4-methoxyphenylacetic acid is used as a versatile reagent in organic synthesis, enabling the construction of complex organic molecules. Its chemical properties and reactivity make it an indispensable component in the synthesis of a broad spectrum of organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 13721-20-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,7,2 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13721-20:
(7*1)+(6*3)+(5*7)+(4*2)+(3*1)+(2*2)+(1*0)=75
75 % 10 = 5
So 13721-20-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H9ClO3/c1-13-8-3-2-6(4-7(8)10)5-9(11)12/h2-4H,5H2,1H3,(H,11,12)
13721-20-5Relevant articles and documents
Preparation method of phenylacetic acid type compound
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Paragraph 0134-0150, (2019/02/21)
The invention discloses a preparation method of a phenylacetic acid type compound. The preparation method of the phenylacetic acid type compound I comprises the following steps that in a solvent and aCO gas phase system, a benzyl halide type compound II, pyridine-2-cobalt carboxylate, palladium acetate and alkaline neutralizers take carbonylation reaction to obtain the phenylacetic acid type compound I. A mixed catalytic system has a synergistic effect; the whole use quantity of catalysts is greatly reduced. When the mixed catalyst is used, a better catalytic effect can be achieved; the characteristics of easily obtaining the catalyst, avoiding the production safety risk of toxic three wastes and the like, reducing the reaction pressure, realizing mild reaction conditions, reducing the production risk, facilitating the production and the like are realized. The formulas are shown in description.
Exalted resonance demands in the substituent effects on the acetolyses of 2-arylethyl trifluoromethanesulfonates destabilized by cn and cf3 groups
Usui, Satoshi,Tsuboya, Shoko,Umezawa, Yukthiro,Hazama, Ken,Okamura, Mutsuo
experimental part, p. 254 - 260 (2009/05/30)
Substituent effects on the acetolysis rates of 2-aryl-l-cyano-l- (trifluoromethyl)ethyl trifluoromethanesulfonates (α-OTf) and 2-aryl-2-cyano-2-(trifluoromethyl)ethyl trifluoromethanesulfonates (ss-OTf) were investigated by using LArSR equation. The obtained p and r+ values were p = -3.28, r+ = 0.98 and p = -3.48,r+ = 0.93 for the acetolysis of α-OTf and ss-OΥi, respectively. The obtained p values are comparable to those for typical aryl-assisted solvolyses, but the r+ values are much larger. The large r+ values suggest that the ester bond cleavages in the deactivated aryl-assisted solvolyses are assisted by the strong participation of the ss-aryl group.
Isoxazole compounds as cyclooxygenase inhibitors
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, (2008/06/13)
A class of substituted isoxazolyl compounds is described for use in treating cyclooxygenase-2 related disorders. Compounds of particular interest are defined by Formula I STR1 wherein R1, R2, and R3, are described in the specification.
