13719-57-8

Basic information

• Product Name: 3-CHLORO-4-METHOXYBENZYL CHLORIDE
• Synonyms: 3-CHLORO-4-METHOXYBENZYL CHLORIDE
• CAS NO: 13719-57-8
• Molecular Formula: C₈H₈Cl₂O
• Molecular Weight: 191.05
• Mol File: 13719-57-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 38 °C
• Boiling Point: 150-200 °C(Press: 12 Torr)
• Appearance: /
• Density: 1.248±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-CHLORO-4-METHOXYBENZYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-4-METHOXYBENZYL CHLORIDE(13719-57-8)
• EPA Substance Registry System: 3-CHLORO-4-METHOXYBENZYL CHLORIDE(13719-57-8)

Safety Data

• Hazardous Substances Data: 13719-57-8(Hazardous Substances Data)

Usage

General Description

3-Chloro-4-methoxybenzyl chloride, also known as 2-(3-Chloro-4-methoxyphenyl)ethyl chloride, is a chemical compound used in the synthesis of various pharmaceutical and agrochemical products. It is a benzyl chloride derivative with a chloro and methoxy substituent on the benzene ring, making it an important building block in organic chemistry. 3-CHLORO-4-METHOXYBENZYL CHLORIDE is primarily used as a reagent in the preparation of various organic compounds, including drugs and other biologically active molecules. Its versatile reactivity and functional group make it a valuable intermediate in the synthesis of complex molecules with important applications in the pharmaceutical and agricultural industries. Additionally, it is also used as a synthetic intermediate in the production of fine chemicals for various industrial processes.

Upstream product

• 4903-09-7 3-chloro-4-methoxy-benzaldehyde 
• 14503-45-8 3-chloro-4-methoxybenzyl alcohol 
• 124-63-0 methanesulfonyl chloride 
• 50-00-0 formaldehyd 
• 766-51-8 2-Chloroanisole 

Downstream Products

• 7569-58-6 2-(3-chloro-4-methoxyphenyl)acetonitrile 
• 55614-55-6 6-(3-Chloro-4-methoxy-phenyl)-5-(3,4-dichloro-phenyl)-2,2-dimethyl-hexan-3-one 
• 60736-66-5 3-chloro-4-(3'-chloro-4'-methoxybenzyloxy)-phenylacetic acid 
• 55614-53-4 6-(3-Chloro-4-methoxy-phenyl)-5-(4-chloro-phenyl)-2,2-dimethyl-hexan-3-one 
• 13721-20-5 2-(3-chloro-4-methoxyphenyl)acetic acid 
• 68119-96-0 1-(3-chloro-4-methoxy-benzyl)-1H-imidazole-4,5-dicarbonitrile 
• 60736-78-9 3-chloro-4-(3'-methyl-4'-isopropoxybenzyloxy)-phenylacetic acid 
• 60736-76-7 3-chloro-4-(4'-isobutoxybenzyloxy)-phenylacetic acid 
• 60736-82-5 3-chloro-4-(4'-isobutylbenzyloxy)-phenylacetic acid 
• 60736-75-6 3-chloro-4-(4' isopropoxy benzyloxy) phenylacetic acid 
• 60736-70-1 3-chloro-4-benzyloxyphenylacetic acid 
• 60736-67-6 3-chloro-4-(3'-chloro-4'-allyloxybenzyloxy)-phenylacetic acid 
• 60736-69-8 3-chloro-4-(3'-chloro-4'-isopropoxybenzyloxy) phenylacetic acid 
• 60736-74-5 3-chloro-4-(4'-allyloxybenzyloxy)-phenylacetic acid 

Relevant articles and documents

Preparation method of avanafil important intermediate

The invention provides a preparation method of an avanafil important intermediate. The target compound (3-chloro-4-methoxybenzylamine) is prepared according to a route shown as the specification. The preparation method provided by the invention has the advantages of cheap and easily available raw materials, short technical route, mild reaction conditions, low equipment requirement, and small health hazard to operators, and is in line with the idea of green chemistry. The method has high yield, and can obtain product with high purity, thus being suitable for industrial production.

Substituted benzyloxyarylacetic acids: synthesis and quantitative relationships between structure and antiinflammatory activity

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