137234-92-5Relevant academic research and scientific papers
1, 3 - DIHYDROXY SUBSTITUTED PHENYLAMIDE GLUCOKINASE ACTIVATORS
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Page/Page column 80-81, (2009/01/24)
Compounds are provided which are glucokinase activators and thus are useful in treating diabetes and related diseases and have the structure wherein in the ring represents one or two double bonds; R1 is alkyl, aryl, arylalkyl, heteroaryl, or he
Antibacterial agents
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, (2008/06/13)
The present invention provides compounds of formula (I): wherein R1-R6 and J and K have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful as antibacterial agents. Also disclosed are pharmaceutical compositions comprising one or more compounds of formula I, processes for preparing compounds of formula I, and intermediates useful for preparing compounds of formula I.
Process for preparing alkyl 3-hydroxy-2, 4, 5-trifluorobenzoates and/or alkyl 3-alkoxy-2, 4, 5-trifluorobenzoates
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, (2008/06/13)
The present invention relates to a process for preparing alkyl 3-hydroxy-2,4,5-trifluorobenzoate and/or alkyl 3-alkoxy-2,4,5-trifluorobenzoate by reacting 3-hydroxy-2,4,5-trifluorobenzoic acid with a dialkyl carbonate at 80° to 200° C.
3-Ethenyl, 3-Ethynyl, 3-Aryl, and 3-Cyclopropyl-2,4,5-Trifluorobenzoic Acids: Useful Intermediates In The Synthesis Of Quinolone Antibacterials
Turner, William R.,Suto, Mark J.
, p. 281 - 284 (2007/10/02)
The synthesis of 3-ethenyl, 3-ethynyl, 3-aryl, and 3-cyclopropyl-2,4,5-trifluorobenzoic acids from 1-bromo-2,4,5-trifluorobenzene and 2,4,5-trifluoro-3-hydroxybenzoic acid is described.These compounds are useful intermediates for the synthesis of quinolon
Quinolinecarboxylic acid antibacterial agents
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, (2008/06/13)
Novel 8-alkenyl, alkynyl, allenyl and cycloalkyl-quinolinecarboxylic acids are described as antibacterial agents as well as methods of manufacture including novel intermediates used in said manufacture.
