137266-59-2

Basic information

• Product Name: 1-benzyl-3,3-bis(chloromethyl)azetidin-2-one
• Synonyms: 1-benzyl-3,3-bis(chloromethyl)azetidin-2-one
• CAS NO: 137266-59-2
• Molecular Weight: 258.147
• Mol File: 137266-59-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-benzyl-3,3-bis(chloromethyl)azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3,3-bis(chloromethyl)azetidin-2-one(137266-59-2)
• EPA Substance Registry System: 1-benzyl-3,3-bis(chloromethyl)azetidin-2-one(137266-59-2)

Safety Data

• Hazardous Substances Data: 137266-59-2(Hazardous Substances Data)

Upstream product

• 813-99-0 3-chloro-(2,2-chloromethyl)propan-1-ol 
• 115-77-5 Pentaerythritol 
• 50547-79-0 3-chloro-2,2-dipropionyl chloride 
• 17831-70-8 3-chloro-2,2-bis(chloromethyl)propionic acid-1 
• 137606-01-0 N-benzyl-3-chloro-2,2-bis(chloromethyl)propanamide 

Downstream Products

• 137266-85-4 1-benzyl-3-chloromethylazetidine-3-carboxylic acid ethyl ester 
• 960079-40-7 6-benzyl-2-phenyl-2,6-diazaspiro[3.3]heptan-1-one 
• 960079-46-3 C₂₀H₂₂N₂O₂ 
• 960079-47-4 2-phenyl-2,6-diazaspiro[3.3]heptan-1-one 
• 959853-29-3 2-benzyl-6-phenyl-2,6-diazaspiro[3.3]heptane 
• 960079-48-5 1-benzyl-3-(chloromethyl)azetidine-3-carboxylic acid 
• 106014-95-3 N-benzyl-3-hydroxymethyl-azetidine-3-carboxylic acid 

Relevant articles and documents

AZETIDINES AS EP2 ANTAGONISTS

The present invention relates to a class of EP2 antagonistazetidinesof general formula (I), wherein the variables and substituents are as defined herein,and especially to EP2 antagonist compounds, to their use in medicine, particularly in the treatment of endometriosis and/or uterine fibroids (leiomyomata)and to intermediates usefulin their synthesis and to compositions containing them.

Concise synthesis of novel 2,6-diazaspiro[3.3]heptan-1-ones and their conversion into 2,6-diazaspiro[3.3]heptanes

A concise synthesis, amenable to library production of 2,6-diazaspiro[3.3] heptan-1-ones and their subsequent conversion into 2,6-diazaspiro[3.3]heptanes is reported. Georg Thieme Verlag Stuttgart.