137606-01-0Relevant articles and documents
AZETIDINES AS EP2 ANTAGONISTS
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Page/Page column 54, (2009/06/27)
The present invention relates to a class of EP2 antagonistazetidinesof general formula (I), wherein the variables and substituents are as defined herein,and especially to EP2 antagonist compounds, to their use in medicine, particularly in the treatment of endometriosis and/or uterine fibroids (leiomyomata)and to intermediates usefulin their synthesis and to compositions containing them.
Concise synthesis of novel 2,6-diazaspiro[3.3]heptan-1-ones and their conversion into 2,6-diazaspiro[3.3]heptanes
Stocks, Michael J.,Hamza, Daniel,Pairaudeau, Garry,Stonehouse, Jeffrey P.,Thorne, Philip V.
, p. 2587 - 2589 (2008/02/13)
A concise synthesis, amenable to library production of 2,6-diazaspiro[3.3] heptan-1-ones and their subsequent conversion into 2,6-diazaspiro[3.3]heptanes is reported. Georg Thieme Verlag Stuttgart.