137348-88-0 Usage
Description
TERT-BUTYL TETRAISOPROPYLPHOSPHORODIAMIDITE is an organic compound that serves as a reagent in various chemical reactions, particularly in the synthesis of aromatic oxophosphorus compounds. It is known for its ability to facilitate the Michaelis-Arbuzov type of reaction of arynes, making it a valuable component in the field of organic chemistry.
Uses
Used in Chemical Synthesis:
TERT-BUTYL TETRAISOPROPYLPHOSPHORODIAMIDITE is used as a reagent for the synthesis of aromatic oxophosphorus compounds through the Michaelis-Arbuzov type of reaction of arynes. This application is significant in the development of new compounds with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, TERT-BUTYL TETRAISOPROPYLPHOSPHORODIAMIDITE is used as a key intermediate in the synthesis of various drug molecules. Its ability to facilitate the Michaelis-Arbuzov type of reaction of arynes allows for the creation of novel compounds with potential therapeutic properties.
Used in Agrochemical Industry:
TERT-BUTYL TETRAISOPROPYLPHOSPHORODIAMIDITE is also utilized in the agrochemical industry for the synthesis of new compounds with pesticidal, herbicidal, or fungicidal properties. The reagent's role in the synthesis of aromatic oxophosphorus compounds contributes to the development of innovative and effective solutions for agricultural challenges.
Used in Materials Science:
In the field of materials science, TERT-BUTYL TETRAISOPROPYLPHOSPHORODIAMIDITE is employed in the synthesis of advanced materials with unique properties, such as improved thermal stability, mechanical strength, or electrical conductivity. The reagent's role in the Michaelis-Arbuzov type of reaction of arynes enables the creation of novel materials with potential applications in various industries, including electronics, aerospace, and automotive.
Check Digit Verification of cas no
The CAS Registry Mumber 137348-88-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,7,3,4 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 137348-88:
(8*1)+(7*3)+(6*7)+(5*3)+(4*4)+(3*8)+(2*8)+(1*8)=150
150 % 10 = 0
So 137348-88-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H37N2OP/c1-12(2)17(13(3)4)20(19-16(9,10)11)18(14(5)6)15(7)8/h12-15H,1-11H3
137348-88-0Relevant articles and documents
Palladium-catalysed amination of aryl- and heteroaryl halides using tert-butyl tetraisopropylphosphorodiamidite as an easily accessible and air-stable ligand
Roiban, Gheorghe-Doru,Mehler, Gerlinde,Reetz, Manfred T.
, p. 2070 - 2076 (2014/04/17)
The phosphorus compound tert-butyl tetraisopropylphosphorodiamidite, prepared from bis(diisopropylamino)chlorophosphine, is an excellent ligand for palladium-catalysed Buchwald-Hartwig amination of aryl- and heteroaryl chlorides and bromides. Based on its ready accessibility and air-stability, this amination protocol is a practical approach to the synthesis of industrially important aryl- and heteroarylamines. Copyright