137371-87-0Relevant academic research and scientific papers
Metal-Free Synthesis of Unsymmetrical Ureas and Carbamates from CO2 and Amines via Isocyanate Intermediates
Ren, Yiming,Rousseaux, Sophie A. L.
, p. 913 - 920 (2018)
A mild and metal-free synthesis of aryl isocyanates from arylamines under an atmosphere of CO2 was developed. The carbamic acid intermediate, derived from the arylamine starting material and CO2 in the presence of DBU, is dehydrated by activated sulfonium reagents to generate the corresponding isocyanate. The latter can be detected by in situ IR and trapped by various amines and alcohols to make unsymmetrical ureas and carbamates, respectively. Dicarbamates can also be prepared in good yields via the mild dehydration of the corresponding dicarbamic acids.
KINETICS OF REACTIONS OF para-SUBSTITUTED PHENYL ISOCYANATES WITH AMINES AND ALCOHOLS
Danihel, Ivan,Barnikol, Falk,Kristian, Pavol
, p. 1662 - 1670 (2007/10/02)
The reaction of para-substituted phenyl isocyanates with amines and alcohols was studied by stopped-flow method.The Hammett correlation obtained showed that the sensitivity of the above mentioned reactions toward substituent effects is the same as that of
