137401-67-3Relevant academic research and scientific papers
Alcohol uncaging with fluorescence reporting: Evaluation of o-acetoxyphenyl methyloxazolone precursors
Gagey, Nathalie,Emond, Matthieu,Neveu, Pierre,Benbrahim, Chouaha,Goetz, Bernard,Aujard, Isabelle,Baudin, Jean-Bernard,Jullien, Ludovic
supporting information; experimental part, p. 2341 - 2344 (2009/06/06)
(Chemical Equation Presented) This paper evaluates a series of photolabile protecting groups with built-in fluorescence reporting. They rely on readily available o-acetoxyphenyl methyloxazolones as activated precursors. Alcohol substrates are easily caged. The resulting photoactivable esters exhibit large one- and two-photon uncaging cross sections. The alcohol substrates are quantitatively released in a 1:1 molar ratio with a strongly fluorescent coumarin coproduct that serves as a reporter to quantify substrate delivery.
4-(2'-Hydroxyphenylmethylene)-2-phenyloxyzol-5(4H)-one: A Comedy of Errors
Cornforth, Sir John,Ming-hui, Du
, p. 2183 - 2187 (2007/10/02)
Eighteen publications since 1955 have described properties and reactions of the title compound.All these reports are erroneous and refer, variously, to three other substances.All literature reports of the analogous 4-(2'-hydroxyphenylmethylene)-2-methyloxazol-5(4H)-one also need revision.A convenient synthesis of the title compound 3 (R=H), its chemical and physical properties, and its rearrangement to 3-benzoylamino-1-benzopyran-2-one 1, are reported here for the first time.A mechanism is presented for the observed course of Ploechl-Erlenmeyer syntheses with salicylaldehyde and with 2-acetoxybenzaldehyde.
