5663-67-2

Basic information

• Product Name: 2-(ACETYLOXY)-BENZALDEHYDE
• Synonyms: 2-(ACETYLOXY)-BENZALDEHYDE;2-Formylphenylacetate,tech;2-formylphenyl acetate
• CAS NO: 5663-67-2
• Molecular Formula: C₉H₈O₃
• Molecular Weight: 164.15802
• Mol File: 5663-67-2.mol
• Article Data: 45

Chemical Properties

• Melting Point: 36-37 °C
• Boiling Point: 272.9°Cat760mmHg
• Flash Point: 118.3°C
• Appearance: /
• Density: 1.183g/cm³
• Vapor Pressure: 0.00592mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: 2-(ACETYLOXY)-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(ACETYLOXY)-BENZALDEHYDE(5663-67-2)
• EPA Substance Registry System: 2-(ACETYLOXY)-BENZALDEHYDE(5663-67-2)

Safety Data

• Hazardous Substances Data: 5663-67-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron, 50, p. 11441, 1994 DOI: 10.1016/S0040-4020(01)89283-8

InChI:InChI=1/C9H8O3/c1-7(11)12-9-5-3-2-4-8(9)6-10/h2-6H,1H3

Upstream product

• 108-24-7 acetic anhydride 
• 90-02-8 salicylaldehyde 
• 634-20-8 1,1-diacetoxy-1-(2-acetoxyphenyl)methane 
• 41390-40-3 2-[(cyclohexylamino)carbonyl]phenyl acetate 
• 108-95-2 phenol 
• 89-95-2 2-methyl-benzyl alcohol 
• 91731-53-2 2-acetoxy-benzoic acid diethylamide 
• 506-96-7 Acetyl bromide 
• 75-36-5 acetyl chloride 
• 90998-02-0 2-methyl-2-phenylthio-1,3-benzodioxan-4-one 
• 89290-01-7 salicylaldehyde, thallium(I) salt 
• 50-78-2 aspirin 
• 463-51-4 Ketene 
• 127-09-3 sodium acetate 

Downstream Products

• 2549-08-8 3-benzamidocoumarin 
• 35175-74-7 (Z)-4-o-acetoxybenzylidene-2-phenyl-4,5-dihydrooxazol-5-one 
• 99056-21-0 2-acetoxy-benzaldehyde-thiosemicarbazone 
• 100381-02-0 2-Acetoxy-benzyliden-bis-chloracetamid 
• 16189-10-9 (E)-3-<2-(acetyloxy)phenyl>-2-propenoic acid 
• 103706-45-2 Acetic acid 2-[1-oxo-1,2-dihydro-benzo[d]pyrrolo[1,2-a]imidazol-(3E)-ylidenemethyl]-phenyl ester 
• 97272-78-1 (2R,4S)-3-Acetyl-2-(2-hydroxyphenyl)-5,5-dimethyl-4-thiazolidincarbonsaeure 
• 97272-79-2 (2S,4S)-3-Acetyl-2-(2-hydroxyphenyl)-5,5-dimethyl-4-thiazolidincarbonsaeure 
• 55210-75-8 2-((E)-3-oxo-3-phenylprop-1-en-1-yl)phenyl acetate 
• 90-02-8 salicylaldehyde 
• 7070-91-9 2-(1',3'-oxathiolan-2'-yl)phenol 
• 30016-55-8 2-[Bis-(2-hydroxy-ethylsulfanyl)-methyl]-phenol 
• 101723-71-1 (E)-2-(3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl)phenyl acetate 
• 17188-40-8 Acetic acid 2-[(2,4-dinitro-phenoxyimino)-methyl]-phenyl ester 

Relevant articles and documents

One-Pot Generation of Benzynes from Phenols: Formation of Primary Anilines by the Deoxyamination of Phenols

Benzynes were selectively generated in situ from phenols and trapped regioselectively with potassium hexamethyldisilazide to form primary anilines following acidic workup. The direct conversion of a phenolic hydroxyl group into a free amino group is a useful method for the preparation of primary aryl amines that are hard to synthesize by using coupling reactions involving phenol derivatives with ammonia. Whereas reactions of ortho- and meta-substituted phenols produced meta-substituted anilines exclusively, those of para-substituted phenols provided ortho-silylanilines.

Synthesis method of 5-(2-bromoacetyl)-2-hydroxybenzaldehyde

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