137417-08-4Relevant articles and documents
Asymmetric synthesis of a dopamine D1 agonist, dihydrexidine from d-serine
Malhotra, Rajesh,Ghosh, Amit,Ghosh, Rajib,Chakrabarti, Sagar,Dutta, Swarup,Dey, Tushar K.,Roy, Subho,Basu, Sourav,Hajra, Saumen
, p. 1522 - 1529 (2011/12/14)
A scalable asymmetric synthesis of trans-2-amino-6,7-dimethoxy-1- phenyltetralin 2 and its N-nosyl derivative 12 have been achieved from Garner aldehyde derived from easily available d-serine using a stereoselective PhMgBr addition, Wittig reaction and TF
A novel and efficient synthesis of dihydrexidine
Cueva, Juan Pablo,Nichols, David E.
body text, p. 715 - 720 (2009/09/06)
An efficient synthesis of the dopamine D1 selective full agonist dihydrexidine has been achieved in high yields and requiring no chromatographic separations via a facilitated intramolecular Henry cyclization of a (nitropropyl)benzophenone and subsequent diastereomerically selective reduction of the resulting tricyclic ni- troalkene. Georg Thieme Verlag Stuttgart.
METHOD OF ADMINISTRATION OF DOPAMINE RECEPTOR AGONISTS
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Page/Page column 33, (2008/06/13)
Methods for treating a patient having pulmonary edema are described. The methods include administering to the lung endobronchial space of the airways of the patient an effective amount of a dopamine D1 receptor agonist. Dopamine D1 receptor agonists, including hexahydrobenzophenanthridine, hexahydrothienophenanthridine, phenylbenzodiazepine, chromenoisoquinoline, naphthoisoquinoline dopamine receptor agonists, and their pharmaceutically acceptable salts, formulated as aerosols and dry powders are also described.