1374787-75-3Relevant academic research and scientific papers
Design, synthesis, molecular docking and biological evaluation of new dithiocarbamates substituted benzimidazole and chalcones as possible chemotherapeutic agents
Bacharaju, Keerthana,Jambula, Swathi Reddy,Sivan, Sreekanth,Jyostnatangeda, Saritha,Manga, Vijjulatha
, p. 3274 - 3277 (2012)
A series of novel dithiocarbamates with benzimidazole and chalcone scaffold have been designed synthesised and evaluated for their antimitotic activity. Compounds 4c and 9d display the most promising antimitotic activity with IC 50 of 1.66 μM and 1.52 μM respectively.
