1374846-36-2Relevant academic research and scientific papers
Design, synthesis and biological evaluations of novel pyridone-thiazole hybrid molecules as antitumor agents
Xie, Wenlin,Wu, Yiqiang,Zhang, Jingai,Mei, Qihong,Zhang, Yahan,Zhu, Ning,Liu, Renzhi,Zhang, Huilin
, p. 35 - 40 (2018/01/10)
A hybrid pharmacophore approach was adopted to design and synthesize new series of pyridone-thiazole hybrid compounds. The structures of the compounds were established by IR, 1H NMR, 13C NMR, and HRMS. All the newly prepared compound
Design and synthesis of novel 5,6-disubstituted pyridine-2,3-dione-3- thiosemicarbazone derivatives as potential anticancer agents
Xie, Wenlin,Xie, Shimin,Zhou, Ying,Tang, Xufu,Liu, Jian,Yang, Wenqian,Qiu, Minghua
, p. 22 - 27 (2014/06/09)
A series of 5,6-disubstituted pyridine-2,3-dione-3-thiosemicarbazone derivatives(2a-2n) and 5,6-disubstituted pyridine-2,3-dione S-benzyl-3- thiosemicarbazones(3a-3g) were synthesized starting from 2,3-dihydroxypyridine via oxidation-Michael additions, co
A facile and efficient iodination of 5,6-di(arylamino)pyridine-2,3-diones
Xie, Wenlin,Zhou, Ying,Xiao, Chuangping,Xie, Ling,Tang, Xufu,Liu, Renyuan
scheme or table, p. 103 - 104 (2012/04/23)
A simple and efficient method for the iodination of 5,6-di(arylamino) pyridine-2,3-diones using iodine with ethanol at room temperature is described. Notable advantages include mild reaction condition, no need for a catalyst, short reaction time, simple practical procedure, giving excellent yield of the product. Iodopyridines have important medical applications as drug or diagnostic aids and radiolabelled compounds.
