137517-69-2

Upstream product

• 73224-22-3 1-methyl-4-(3-methoxyphenyl)-1,2,3,6-tetrahydropyridine 
• 377730-71-7 trifluoro-methanesulfonic acid 3-allyl-1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl ester 
• 377730-72-8 3-allyl-4-(3-methoxy-phenyl)-1-methyl-1,2,3,6-tetrahydro-pyridine 
• 41191-02-0 3-allyl-N-methyl-4-piperidinone 
• 137517-93-2 (+/-)-2,3,4,4a,5,8-hexahydro-4a-(3-methoxyphenyl)-2-methylisoquinoline 

Downstream Products

• 137517-71-6 3-((4aR,8aR)-2-Methyl-1,3,4,5,8,8a-hexahydro-2H-isoquinolin-4a-yl)-phenol 

Relevant academic research and scientific papers

Ring closing metathesis mediated synthesis of 4a-aryloxodecahydroisoquinolines, intermediates in the preparation of novel opiates

(matrix presented) The concise syntheses of the 4a-aryldecahydroisoquinolines 1 and 2 through a uniform strategy starting from N-methyl-3-allyl-4-piperidinone are reported in this Letter. Key transformations include a ring closing metathesis reaction to p

Synthesis, Antinociceptive Activity, and Opioid Receptor Profiles of Substituted trans-3-(Decahydro- and Octahydro-4a-isoquinolinyl)phenols

A series of trans-3-(6- and 7-substituted-decahydro-4a-isoquinolinyl)phenols and trans-3-(octahydro-4a-isoquinolinyl)phenols have been synthesized as potential opioid analgesics.Using a combination of in vitro and in vivo test systems, the receptor profil