137522-23-7

Upstream product

• 83685-95-4 [(2E,4E,8Z)-6-(tert-Butyl-dimethyl-silanyloxy)-tetradeca-2,4,8-trienyl]-triphenyl-phosphonium; bromide 
• 82493-58-1 6-ethoxy-1,6-dioxohexan-2-yl benzoate 
• 22900-10-3 2-deoxy-D-ribose 
• 82493-54-7 (2E,4E,8Z)-6-Hydroxy-tetradeca-2,4,8-trienoic acid ethyl ester 
• 132131-38-5 (2E,4E,8Z)-6-(tert-Butyl-dimethyl-silanyloxy)-tetradeca-2,4,8-trien-1-ol 
• 83685-93-2 (2E,4E,8Z)-6-(tert-Butyl-dimethyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester 
• 82493-52-5 ethyl tetrahydro-4(S)-<(tert-butyldimethylsilyl)oxy>-5(R)-(2-octenyl)-2-furanacetate 
• 82493-53-6 [(4S,5R)-4-Methanesulfonyloxy-5-((Z)-oct-2-enyl)-tetrahydro-furan-2-yl]-acetic acid ethyl ester 
• 79308-40-0 (E)-(5R,6S)-5,6,7-Trihydroxy-hept-2-enoic acid ethyl ester 
• 79308-52-4 ethyl 2-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]acetate 
• 82493-51-4 ethyl tetrahydro-4(S)-<(tert-butyldimethylsilyl)oxy>-5(S)-(iodomethyl)-2-furanacetate 
• 92007-81-3 Benzoic acid (R)-1-((S)-1,2-dihydroxy-ethyl)-4-ethoxycarbonyl-butyl ester 
• 98-88-4 benzoyl chloride 
• 82493-58-1 ethyl 2-O benzoyl-3,4,5-trideoxy-L-glycero-hexuronate 

Downstream Products

• 82493-60-5 (5S,12R,6Z,8E,10E,14Z)-ethyl 5-benzoyloxy-12-hydroxyicosatetra-6,8,10,14-enoate 
• 71160-24-2 Leukotriene B 
• 70578-51-7 (6Z,8E,10E,14Z)-(5S,12R)-5,12-Dihydroxy-icosa-6,8,10,14-tetraenoic acid 
• 82493-60-5 Benzoic acid (2Z,4E,6E,10Z)-(1S,8R)-1-(3-ethoxycarbonyl-propyl)-8-hydroxy-hexadeca-2,4,6,10-tetraenyl ester 

Relevant academic research and scientific papers

Use of the Two Enantiometers of 7,7-Dimethylbicyclohept-2-en-6-one to form Complementary Optically Active Synthons in a Convergent Synthesis of Leukotriene-B4

The acetate (+/-)-4 was resolved by an enantioselective hydrolysis catalysed by porcine pancreatic lipase.The resultant alcohol (-)-3 and the optically active ester (+)-4 were converted into the ketones (+)-2 and (-)-2 respectively.The ketone (+)-2 was el

STEREOSPECIFIC SYNTHESIS OF LEUKOTRIENE B4 (LTB4)

A stereospecific and chirally economical synthesis of LTB4 starting from 2-deoxy-D-ribose is reported as part of a comprehensive and efficient approach to the Leukotrienes (A, B, C, D, E).The process includes a novel approach to chiral dienic synthons.