83685-95-4

Upstream product

• 132131-38-5 (2E,4E,8Z)-6-(tert-Butyl-dimethyl-silanyloxy)-tetradeca-2,4,8-trien-1-ol 
• 137522-16-8 (2R,5S) and (2S,5S)-tetrahydro-5-(3-methylbut-2-enyl)furan-2-ol 
• 137522-18-0 (3S,5Z)-1-(1,3-dithiolan-2-yl)undec-5-en-3-ol 
• 132201-59-3 (6R,2E,4E,8Z)-methyl 6-(tert-butyldimethylsilyloxy)tetradeca-2,4,8-trienoate 
• 132131-35-2 (2R,5S) and (2S,5S)-tetrahydro-2-(tert-butyldimethylsilyloxy)-5-<(Z)-oct-2-enyl>furan 
• 137522-17-9 (2R,5S) and (2S,5S)-tetrahydro-2-(tert-butyldimethylsilyloxy)-5-(3-methylbut-2-enyl)furan 
• 127056-35-3 (2R,5S) and (2S,5S)-tetrahydro-2-(tert-butyldimethylsilyloxy)-5-(2-oxoethyl)furan 
• 4762-26-9 hexyltriphenylphosphonium bromide 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 132131-39-6 (6R,2E,4E,8Z)-1-bromo-6-(tert-butyldimethylsilyloxy)tetradeca-2,4,8-triene 
• 603-35-0 triphenylphosphine 
• 82493-51-4 ethyl tetrahydro-4(S)-<(tert-butyldimethylsilyl)oxy>-5(S)-(iodomethyl)-2-furanacetate 
• 79308-52-4 ethyl 2-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]acetate 
• 79308-40-0 (E)-(5R,6S)-5,6,7-Trihydroxy-hept-2-enoic acid ethyl ester 

Downstream Products

• 137522-23-7 (5S,12R,6Z,8E,10E,14Z)-ethyl 5-benzoyloxy-12-(tert-butyldimethylsilyloxy)icosatetra-6,8,10,14-enoate 
• 137522-23-7 (5S,12R,6E,8E,10E,14Z)-ethyl 5-benzoyloxy-12-(tert-butyldimethylsilyloxy)icosatetra-6,8,10,14-enoate 
• 82493-60-5 (5S,12R,6Z,8E,10E,14Z)-ethyl 5-benzoyloxy-12-hydroxyicosatetra-6,8,10,14-enoate 
• 71160-24-2 Leukotriene B 
• 70578-51-7 (6Z,8E,10E,14Z)-(5S,12R)-5,12-Dihydroxy-icosa-6,8,10,14-tetraenoic acid 
• 82493-60-5 Benzoic acid (2Z,4E,6E,10Z)-(1S,8R)-1-(3-ethoxycarbonyl-propyl)-8-hydroxy-hexadeca-2,4,6,10-tetraenyl ester 
• 137522-23-7 Benzoic acid (2E,4E,6E,10Z)-(1S,8R)-8-(tert-butyl-dimethyl-silanyloxy)-1-(3-ethoxycarbonyl-propyl)-hexadeca-2,4,6,10-tetraenyl ester 
• 137522-23-7 Benzoic acid (2Z,4E,6E,10Z)-(1R,8R)-8-(tert-butyl-dimethyl-silanyloxy)-1-(3-ethoxycarbonyl-propyl)-hexadeca-2,4,6,10-tetraenyl ester 

Relevant academic research and scientific papers

Use of the Two Enantiometers of 7,7-Dimethylbicyclohept-2-en-6-one to form Complementary Optically Active Synthons in a Convergent Synthesis of Leukotriene-B4

The acetate (+/-)-4 was resolved by an enantioselective hydrolysis catalysed by porcine pancreatic lipase.The resultant alcohol (-)-3 and the optically active ester (+)-4 were converted into the ketones (+)-2 and (-)-2 respectively.The ketone (+)-2 was el

STEREOSPECIFIC SYNTHESIS OF LEUKOTRIENE B4 (LTB4)

A stereospecific and chirally economical synthesis of LTB4 starting from 2-deoxy-D-ribose is reported as part of a comprehensive and efficient approach to the Leukotrienes (A, B, C, D, E).The process includes a novel approach to chiral dienic synthons.