13771-68-1

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 5-bromo-1-benzothiophene-2-carboxylate is used as a pharmacologically active compound for its potential therapeutic applications. It is being studied for its ability to modulate various biological pathways and target specific diseases, making it a promising candidate for the development of new drugs and therapies.
Used in Chemical Research:
In the field of chemical research, Ethyl 5-bromo-1-benzothiophene-2-carboxylate serves as a valuable intermediate for the synthesis of more complex molecules and compounds. Its unique structure and functional groups make it an attractive building block for the creation of novel chemical entities with potential applications in various industries.
Used in Material Science:
Ethyl 5-bromo-1-benzothiophene-2-carboxylate may also find applications in material science, particularly in the development of new materials with specific properties. Its chemical structure can be utilized to create materials with tailored characteristics, such as improved stability, enhanced reactivity, or unique optical and electronic properties.

Upstream product

• 61072-56-8 4-chloro-2-fluorobenzaldehyde 
• 623-51-8 ethyl 2-sulfanylacetate 
• 7312-10-9 5-bromo-1-benzothiophene-2-carboxylic acid 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 

Downstream Products

• 13771-72-7 (5-bromobenzo[b]thiophen-2-yl)methanol 
• 907945-16-8 ethyl 5-(4-chlorophenyl)-1-benzothiophene-2-carboxylate 
• 907945-18-0 ethyl 5-[4-(trifluoromethyl)phenyl]-1-benzothiophene-2-carboxylate 
• 907945-22-6 ethyl 5-(4-methoxyphenyl)-1-benzothiophene-2-carboxylate 
• 907945-25-9 ethyl 5-[3-(acetylamino)phenyl]-1-benzothiophene-2-carboxylate 
• 907945-27-1 ethyl 5-(pyridin-3-yl)-1-benzothiophene-2-carboxylate 
• 907945-29-3 ethyl 5-[4-(dimethylamino)phenyl]-1-benzothiophene-2-carboxylate 
• 907945-53-3 ethyl 5-(4-isopropoxyphenyl)-1-benzothiophene-2-carboxylate 
• 907945-57-7 ethyl 5-(4-methylphenyl)-1-benzothiophene-2-carboxylate 
• 50638-17-0 5-Bromo-2-chloromethyl-benzo[b]thiophene 
• 105191-14-8 5-Cyanbenzothiophen-2-carbonsaeure-ethylester 
• 38251-66-0 5-bromobenzo[b]thiophene-2-carbonitrile 
• 7312-18-7 5-bromobenzo[b]thiophene-2-carboxaldehyde 

Relevant academic research and scientific papers

INHIBITORS OF PLASMA KALLIKREIN AND USES THEREOF

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

Benzothiophene-flanked diketopyrrolopyrrole polymers: Impact of isomeric frameworks on carrier mobilities

Exploring new building blocks for solution-processable polymeric semiconductors has attracted much attention. We herein develop two isomeric benzothiophene-flanked diketopyrrolopyrrole polymers with different linkage positions and further systematically study the electronic structures, optical properties, and field-effect characteristics. Both polymers exhibit typical p-type transport characteristics with the highest mobility being up to 0.80 cm2 V-1 s-1. Our results suggest that the isomeric backbones for conjugated polymers greatly affect charge transport properties.

MODULATORS FOR NICOTINIC ACETYLCHOLINE RECEPTOR α2 AND α4 SUBUNITS

Positive allosteric modulators (PAMs) of nicotinic acetylcholine receptors (nAChR) are important therapeutic candidates as well as valuable research tools. We identified a novel type II PAM, (R)-7-bromo-N-(piperidin-3-yl)benzo[b]thiophene-2-carboxamide (B

Novel 1-Heteroaryl-3-Azabicyclo[3.1.0]Hexanes Methods For Their Preparation And Their Use As Medicaments

The invention provides novel 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, and related processes and intermediates for preparing these compounds, as well as compositions and methods employing these compounds for the treatment and/or prevention of central nervo

AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR

The present invention provides a GPR receptor function regulator comprising the compound represented by the formula: [wherein ring A is an optionally substituted isocyclic or heterocyclic ring, P is a bond or spacer, ring D is an optionally substituted monocyclic aromatic ring which may be condensed with a 5-to 7-membered ring, V is a bond or the group represented by the formula -CR14=CR15 - or - N=CR16- (wherein R14, R15 and R16 each represents a hydrogen atom or optionally substituted hydrocarbon group), Q is a bond or spacer, and W is a carboxyl or a group biologically equivalent to a carboxyl] or its salt or a prodrug thereof

Aromatic amidine derivatives useful as selective thrombin inhibitors

The present invention relates to a novel thrombin inhibitor which is effective even when orally administered. More specifically, the present invention relates to an aromatic amidine derivative represented by formula (I) and the salts thereof, which show potent selective inhibitory activity for thrombin in which (a), R, R1, R2, R3, A, W, Y and n are defined as described in the specification.

AROMATIC AMIDINE DERIVATIVES AND SALTS THEREOF

An anticoagulant agent which comprises, as an active ingredient, an aromatic amidine derivative represented by the following general formula (1) or a salt thereof: STR1 wherein the group represented by STR2 is a group selected from indolyl, benzofuranyl, benzothienyl, benzimidazolyl, benzoxazolyl, benzothiazolyl, naphthyl, tetrahydronaphthyl and indanyl; X is a single bond, an oxygen atom, a sulfur atom or a carbonyl group; and Y is a saturated or unsaturated 5-or 6-membered heterocyclic moiety or cyclic hydrocarbon moiety optionally having a substituent group, an amino group optionally having a substituent group or an aminoalkyl group optionally having a substituent group.The inventive compound has a high anticoagulant capacity based on its excellent FXa inhibition activity.