138007-25-7

Basic information

• Product Name: Butanoic acid, 4-(methylamino)-, 1,1-dimethylethyl ester
• CAS NO: 138007-25-7
• Molecular Formula: C9H19NO2
• Molecular Weight: 173.255
• Mol File: 138007-25-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 4-(methylamino)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4-(methylamino)-, 1,1-dimethylethyl ester(138007-25-7)
• EPA Substance Registry System: Butanoic acid, 4-(methylamino)-, 1,1-dimethylethyl ester(138007-25-7)

Safety Data

• Hazardous Substances Data: 138007-25-7(Hazardous Substances Data)

Usage

General Description

Butanoic acid, 4-(methylamino)-, 1,1-dimethylethyl ester, also known as t-butyl 4-(methylamino)butanoate, is an organic compound with the chemical formula C10H21NO2. It is a colorless to pale yellow liquid with a fruity odor, commonly used as a flavoring agent in the food industry. It is often found in products such as fruit-flavored beverages, chewing gum, and baked goods. Its main use is as a flavoring agent, providing a fruity, pineapple-like aroma and taste. Butanoic acid, 4-(methylamino)-, 1,1-dimethylethyl ester is also used in the production of fragrances and as a precursor in the synthesis of various pharmaceuticals and other chemicals. It is important to handle and use this compound with caution, as it can be irritating to the skin, eyes, and respiratory system.

Upstream product

• 1366733-87-0 4-(Fmoc-N-methylamido)butanoate t-butyl ester 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 1119-48-8 4-(methylamino)butyric acid 
• 98008-66-3 4-{[(benzyloxy)carbonyl](methyl)amino}butanoic acid 
• 229009-12-5 tert-butyl 4-{[(benzyloxy)carbonyl](methyl)amino}butanoate 

Downstream Products

• 1600526-59-7 tert-butyl 4-((4-hydroxy-3,6-dioxo-5-tridecylcyclohexa-1,4-dienyl)(methyl)amino)-butanoate 
• 1600526-60-0 tert-butyl 4-((4-methoxy-3,6-dioxo-5-tridecylcyclohexa-1,4-dienyl)(methyl)amino)-butanoate 
• 229009-13-6 tert-butyl 4-[(4-bromo-2-formylphenyl)(methyl)amino]butanoate 

Relevant articles and documents

MULTIFUNCTIONAL RADICAL QUENCHERS

The invention provides a compound of formula (I): [insert formula (I)] wherein X, Y, and R1-R4 have any of the values defined in the specification, and salts thereof, as well as compositions comprising the compounds or salts. The compounds are useful for treating diseases associated with impaired mitochondrial function in an animal.

Synthesis of 1-benzothiepine and 1-benzazepine derivatives as orally active CCR5 antagonists

Quaternary ammonium benzocycloheptene compound 1 has previously been reported as a clinical candidate for an injectable CCR5 antagonist. In order to develop an orally active CCR5 antagonist, derivatives of tertiary amine benzocycloheptene 2, the chemical precursor to 1, were investigated. The benzocycloheptene ring was converted to benzothiepine and benzazepine rings and it was found that these changes could enhance the potency of tertiary amine derivatives. In particular, the 1-benzothiepine-1,1-dioxide 11b and the N-methyl-1-benzazepine 18 showed increased activity and good preliminary pharmacokinetic properties. The synthesis of 1-benzothiepine and 1-benzazepine derivatives and their activity are described.