138022-02-3

Basic information

• Product Name: 4-[(METHYLAMINO)METHYL]PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 4-[(METHYLAMINO)METHYL]PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;TERT-BUTYL 4-[(METHYLAMINO)METHYL]PIPERIDINE-1-CARBOXYLATE;1-N-BOC-4-[(METHYLAMINO)METHYL]PIPERIDINE;1-Piperidinecarboxylic acid, 4-[(methylamino)methyl]-, 1,1-dimethylethyl ester;1-piperidinecarboxylic acid, 4-[(methylamino)methyl]-, 1,1;tert-butyl 4-[(methylamino)methyl]piperidine-1-carboxylate - oxalate (2:1);1-Boc-4-[(Methylamino)methyl]piperidine;tert-butyl 4-[(methylamino)methyl]-1-piperidinecarboxylate(SALTDATA: FREE)
• CAS NO: 138022-02-3
• Molecular Formula: C₁₂H₂₄N₂O₂
• Molecular Weight: 228.33
• Product Categories: Aminomethyl's;Pyrans, Piperidines &Piperazines;Pyrans, Piperidines & Piperazines
• Mol File: 138022-02-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 300.981 °C at 760 mmHg
• Flash Point: 135.829 °C
• Appearance: /
• Density: 0.988
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.469
• Storage Temp.: 2-8°C(protect from light)
• PKA: 10.41±0.10(Predicted)
• CAS DataBase Reference: 4-[(METHYLAMINO)METHYL]PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(METHYLAMINO)METHYL]PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(138022-02-3)
• EPA Substance Registry System: 4-[(METHYLAMINO)METHYL]PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(138022-02-3)

Safety Data

• Statements: 36737/38
• Safety Statements: 26-36
• Hazardous Substances Data: 138022-02-3(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

InChI:InChI=1/C12H24N2O2/c1-12(2,3)16-11(15)14-7-5-10(6-8-14)9-13-4/h10,13H,5-9H2,1-4H3

Upstream product

• 544696-01-7 tert-butyl 4-(methylcarbamoyl)piperidine-1-carboxylate 

Downstream Products

• 1392888-98-0 C₂₄H₃₂N₈S 
• 1313732-78-3 methyl-[6-methyl-3-(3-trifluoromethoxy-phenyl)-7,8-dihydro-6H-9-oxa-1,2,3a,4,6-pentaaza-cyclopenta[a]naphthalen-5-yl]-piperidin-4-ylmethyl-amine 
• 1313732-77-2 methyl-{1-[6-methyl-3-(3-trifluoromethoxy-phenyl)-7,8-dihydro-6H-9-oxa-1,2,3a,4,6-pentaaza-cyclopenta[a]naphthalen-5-yl]-piperidin-4-ylmethyl}-amine 

Relevant articles and documents

NEW PYRIDAZINE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS

The present invention relates to compounds of general formula I wherein the groups and radicals B, W, X, Y, Z, R1, R2, have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.

Fused imidazopyridine derivatives as antihyperlipidemic agents

A novel compound of the formula: wherein ring Q is an optionally substituted pyridine ring; One of R0, R1and R2is —Y0—Z0, and the other tow groups are a hydrogen, a halogen, an optionally substituted hydroxy group, a hydrocarbon group that may be an optionally substituted hydrocarbon group or an acyl group; Y0is a bond or an optionally substituted bivalent hydrocarbon group; Z0is a basic group which may be bonded via oxygen, nitrogen, —CO—, —CS—, —SO2N(R3)— (where R3is hydrogen or an optionally substituted hydrocarbon group), or S(O)n(wherein n is to 0, 1 or 2); .........is a single bond or a double bond, or a salt thereof, which has an excellent LDL receptor up-regulating, blood-lipids lowering, blood-sugar lowering and diabetic complication-ameliorating activity.