138110-77-7

Basic information

• Product Name: Benzene, 1-(3-iodo-1-phenylpropoxy)-4-(trifluoromethyl)-, (R)-
• CAS NO: 138110-77-7
• Molecular Formula: C16H14F3IO
• Molecular Weight: 406.186
• Mol File: 138110-77-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(3-iodo-1-phenylpropoxy)-4-(trifluoromethyl)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(3-iodo-1-phenylpropoxy)-4-(trifluoromethyl)-, (R)-(138110-77-7)
• EPA Substance Registry System: Benzene, 1-(3-iodo-1-phenylpropoxy)-4-(trifluoromethyl)-, (R)-(138110-77-7)

Safety Data

• Hazardous Substances Data: 138110-77-7(Hazardous Substances Data)

Upstream product

• 402-45-9 4-hydroxybenzotrifluoride 
• 115290-77-2 (1S) 3-phenyl-3-hydroxypropyl methanesulfonate 
• 138110-76-6 (R)-3-(4-trifluoromethylphenoxy)-3-phenylprop-1-yl methanesulfonate 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 96854-34-1 (S)-3-phenyl-1,3-propanediol 
• 33401-74-0 ethyl (3R)-3-hydroxy-3-phenylpropionate 

Downstream Products

• 114247-09-5 (R)-fluoxetine hydrochloride 
• 54910-89-3 (R)-fluoxetine 

Relevant articles and documents

Asymmetric Synthesis of Both Enantiomers of Fluoxetine via Microbiological Reduction of Ethyl Benzoylacetate

Microbiological reduction of ethyl benzoylacetate by bakers' yeast (Saccharomyces cerevisiae), Beauveria sulfurescens or Geotrichum candidum afforded ethyl (S)-3-hydroxy-3-phenylpropionate in high optical yield.This enantiomerically pure alcohol was converted into both enantiomers of fluoxetine (7).The product resulting from the bakers' yeast reduction had ee values (87-93percent) lower than the 100percent value erroneously attributed in earlier studies.Key Words: Fluoxetine; asymmetric synthesis; bioreduction; bakers' yeast; Beauveria sulfurescens; Geotrichum candidum.