138181-67-6Relevant academic research and scientific papers
ANTIBODY CONJUGATES AND METHODS OF MAKING THE ANTIBODY CONJUGATES
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Paragraph 0193, (2017/01/02)
Described herein are antibody conjugates and methods of making antibody conjugates.
Intramolecular aglycon delivery for (1 → 2)-β-mannosylation: Towards the synthesis of phospholipomannan of Candida albicans
Gannedi, Veeranjaneyulu,Ali, Asif,Singh, Parvinder Pal,Vishwakarma, Ram A.
supporting information, p. 2945 - 2947 (2014/05/06)
A high yielding method for 1,2-cis-β-D-mannosylation by intra-molecular aglycon delivery (IAD) through p-methoxy benzyl ether/acetal exchange and phenylsulfoxide donor is reported, along with its application in iterative assembly of antigenic (1 → 2)-β-pe
Synthesis of the repeating trisaccharide unit of the cell wall lipopolysaccharide of Escherichia coli type 8
Maity, Sajal K.,Maity, Swarupananda,Patra, Amarendra,Ghosh, Rina
scheme or table, p. 5847 - 5849 (2009/04/05)
NIS/TfOH mediated glycosidation of methyl 3,4,6-tri-O-benzyl-α-d-mannopyranoside with phenyl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-α-d-mannopyranoside furnished the corresponding disaccharide derivative in excellent yield and α-selectivity. Ze?mplen deacet
Inositolphosphoglycan mediators structurally related to glycosyl phosphatidylinositol anchors: Synthesis, structure and biological activity
Martin-Lomas, Manuel,Khiar, Noureddine,Garcia, Salud,Koessler, Jean-Luc,Nieto, Pedro M.,Rademacher, Thomas W.
, p. 3608 - 3621 (2007/10/03)
The preparation of the pseudopentasaccharide 1a, an inositolphosphoglycan (IPG) that contains the conserved linear structure of glycosyl phosphatidylinositol anchors (GPI anchors), was carried out by using a highly convergent 2+3-block synthesis approach which involves imidate and sulfoxide glycosylation reactions. The preferred solution conformation of this structure was determined by using NMR spectroscopy and molecular dynamics simulations prior to carrying out quantitative structure-activity relationship studies in connection with the insulin signalling process. The ability of 1a to stimulate lipogenesis in rat adipocites as well as to inhibit cAMP dependent protein kinase and to activate pyruvate dehydrogenase phosphatase was investigated. Compound 1a did not show any significant activity, which may be taken as a strong indication that the GPI anchors are not the precursors of the IPG mediators.
1,2-cis-c-glycoside synthesis by samarium diiodide-promoted radical cyclizations
Skrydstrup, Troels,Mazeas, Daniel,Elmouchir, Mohamed,Doisneau, Gilles,Riche, Claude,Chiaroni, Angele,Beau, Jean-Marie
, p. 1342 - 1356 (2007/10/03)
The samarium diiodide reduction of glycosyl pyridyl sulfones bearing a silicon-tethered unsaturated group at the C2-OH position leads to the stereo-specific synthesis of 1,2-cis-C-glycosides in good yield after desilylation. These reactions proceed via an
Glycosylation using a one-electron-transfer, homogeneous reagent. Application to an efficient synthesis of the trimannosyl core of N-glycosylproteins
Zhang, Yong-Min,Mallet, Jean-Maurice,Sinay, Pierre
, p. 73 - 88 (2007/10/02)
Double glycosylation of methyl 2,4-di-O-benzyl-β-D-mannopyranoside with ethyl 2-O-benzoyl-3,4,6-tri-O-benzyl-1-thio-α-D-mannopyranoside using as promoter tris(4-bromophenyl)ammoniumyl hexachloroantimonate, a stable, commercial, and crystalline radical cat
