1383568-93-1

Basic information

• Product Name: (S,E)-(3-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1H-indol-2-yl)methanone
• Synonyms: (S,E)-(3-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1H-indol-2-yl)methanone
• CAS NO: 1383568-93-1
• Molecular Weight: 374.483
• Mol File: 1383568-93-1.mol

Chemical Properties

• CAS DataBase Reference: (S,E)-(3-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1H-indol-2-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (S,E)-(3-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1H-indol-2-yl)methanone(1383568-93-1)
• EPA Substance Registry System: (S,E)-(3-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1H-indol-2-yl)methanone(1383568-93-1)

Safety Data

• Hazardous Substances Data: 1383568-93-1(Hazardous Substances Data)

Upstream product

• 40899-71-6 1-benzenesulfonylindole 
• 1383568-89-5 (S,E)-3-ethylidene-1-(4-methoxybenzyl)piperidine-4-carbaldehyde 
• 824-94-2 p-methoxybenzyl chloride 
• 40900-03-6 1-(benzenesulfonyl)-2-lithioindole 
• 1383568-91-9 ((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1H-indol-2-yl)methanol 
• 1383568-90-8 ((S,E)-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)(1-(phenylsulfonyl)-1H-indol-2-yl)methanol 
• 1312678-79-7 (+/-)-1-(N-(4-methoxybenzyl)-1,2,5,6-tetrahydropyridin-3-yl)ethanol 
• 1383568-87-3 (S,E)-(3-ethylidene-1-(4-methoxybenzyl)piperidin-4-yl)methanol 
• 1383568-86-2 (S)-1-(4-methoxybenzyl)-5-(1-((tributylstannyl)methoxy)ethyl)-1,2,3,6-tetrahydropyridine 
• 1312678-77-5 (S)-1-(N-(4-methoxybenzyl)-1,2,5,6-tetrahydropyridin-3-yl)ethanol 
• 4754-27-2 1-(3-Pyridyl)ethanol 

Relevant articles and documents

Discovery of conolidine derivative DS39201083 as a potent novel analgesic without mu opioid agonist activity

We discovered a novel compound, 5-methyl-1,4,5,7-tetrahydro-2,5-ethanoazocino[4,3-b]indol-6(3H)-one sulfuric acid salt (DS39201083), which was formed by derivatization of a natural product, conolidine. DS39201083 had a unique bicyclic skeleton and was a m

SYNTHESIS OF CONOLIDINE AND DISCOVERY OF A POTENT NON-OPIOID ANALGESIC FOR PAIN

The first de novo synthetic pathway to the exceptionally rare C5-nor stemmadenine natural product, conolidine, and the first asymmetric synthesis of any member of this natural product class arc described. C5-nor stemmadenine compositions are also describe

Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain

Management of chronic pain continues to represent an area of great unmet biomedical need. Although opioid analgesics are typically embraced as the mainstay of pharmaceutical interventions in this area, they suffer from substantial liabilities that include